Results 51 to 60 of about 66,412 (255)

Efficacy of Generalized Face Masking Mandates

open access: yesHealth Services Research & Managerial Epidemiology, 2021
This commentary discusses if targeted uses of face masks may provide better results than generalized face masks mandates to limit the spread of Covid-19.
Alberto Boretti
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Accuracy and precision in DM intake prediction models for lactating dairy cows

open access: yesAnimal
Predicting the daily DM intake (DMI) of lactating dairy cows is an essential criterion for formulating diets according to requirements, which limits the application of safety margins in economically and environmentally sensitive nutrients, such as energy,
N. Mehaba   +4 more
doaj   +1 more source

The unfunded mandates in local governments financing crises experiences from Estonia. Finantskatteta ülesanded kohalike omavalitsuste finantsides: kriisikogemused Eestist

open access: yesEesti Majanduspoliitilised Väitlused, 2015
In many countries occur problems from unfunded mandates related to a shift of a function by an upper tier of government to lower rank governments without providing the lower one with financial means to perform these functions.
Peter Friedrich, Janno Reiljan
doaj   +1 more source

Problems of substituting vacant deputy’s mandates due to early termination of powers of a deputy elected within a list of candidates

open access: yesИзвестия высших учебных заведений. Поволжский регион: Общественные науки, 2022
Background. The distribution of deputy mandates after the end of the elections is one of the most controversial issues in legal science. The use of various methods of mandate distribution directly determines the implementation of electoral rights.
M.Yu. Emelin, B.V. Nikolaev
doaj   +1 more source

Vaccine Mandates, Private Incentives and the Efficient Use of Coronavirus Vaccines

open access: yesWirtschaftsdienst, 2022
From an economic point of view, vaccine mandates are a negative incentive to get vaccinated. Positive incentives that induce unvaccinated individuals just as effectively — such as government-provided cash incentives — can be more flexible and avoid some ...
Michael Stolpe
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht   +53 more
wiley   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

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