Results 181 to 190 of about 468,586 (280)

Principles for Rigorous Design and Application of Synthetic Microbial Communities

open access: yesAdvanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang   +21 more
wiley   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

open access: yesAdvanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan   +12 more
wiley   +1 more source

Tiny lives, big failures: India's drug regulation crisis. [PDF]

open access: yesLancet Reg Health Southeast Asia
The Lancet Regional Health-Southeast Asia.
europepmc   +1 more source

HSP90AB1‐Mediated Ubiquitin‐Proteasome Degradation of ITGBL1 Promotes Osteosarcoma Progression by Inhibiting Endoplasmic Reticulum Stress‐Induced Autophagy

open access: yesAdvanced Science, EarlyView.
This study delineates a novel HSP90AB1‐ITGBL1 signaling axis governing osteosarcoma. HSP90AB1 promotes K63‐linked ubiquitination and proteasomal degradation of ITGBL1. Restoring ITGBL1 induces reactive oxygen species‐dependent endoplasmic reticulum stress and pro‐death autophagy, suppressing tumor growth and metastasis.
Zhen Wang   +17 more
wiley   +1 more source

Multi‐Dimensional Acoustic Cascaded Holographic Encryption with Instantaneous Visual Decryption via Particle Manipulation

open access: yesAdvanced Science, EarlyView.
Acoustic holograms act as key tools for information encryption, yet current schemes limit encryption dimensionality/security and require time‐consuming decryption. A compact device integrates multi‐dimensional cascaded acoustic holography with particle manipulation, employs extra secret keys, enables rapid decryption, and is validated via 1D/2D/3D ...
Qin Lin   +8 more
wiley   +1 more source

Volume isn't openness: misaligned assessment and Open Science adoption in Ecuador. [PDF]

open access: yesFront Res Metr Anal
Guerra J   +2 more
europepmc   +1 more source

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