Results 41 to 50 of about 475,187 (298)

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

Testing the Finch Hypothesis on Green OA Mandate Ineffectiveness [PDF]

open access: yes, 2012
We have now tested the Finch Committee's Hypothesis that Green Open Access Mandates are ineffective in generating deposits in institutional repositories.
Brody, Tim   +5 more
core   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

The Impact and Dilemma of Unfunded Mandates Confronting Local Government South Africa: A Comparative Analysis

open access: yesAfrica’s Public Service Delivery & Performance Review, 2012
Local government has emerged from a prolonged transition to face a second generation of challenges, namely unfunded mandates. Compliance with the current financial management system is a constant challenge for local government.
M. Basdeo
doaj   +1 more source

Choosing Financial Regulatory Agency Mandates [PDF]

open access: yes, 2009
Outlines four approaches to dividing the responsibilities of federal financial regulatory agencies: institutional regulation, functional regulation, regulation by objective, and an integrated approach.
Charles Taylor
core  

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

Trading-Off Reproductive Technology and Adoption: Does Subsidizing in Vitro Fertilization Decrease Adoption Rates and Should It Matter? [PDF]

open access: yes, 2010
For those facing infertility, using assisted reproductive technology to have genetically related children is a very expensive proposition. In particular, to produce a live birth through in vitro fertilization (IVF) will cost an individual (on average ...
Chen, Daniel L., Cohen, I. Glenn
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

CONTEMPORARY U.S. FEDERALISM: COERCIVE CHANGE WITH COOPERATIVE CONTINUITY [PDF]

open access: yesRevista d'Estudis Autonòmics i Federals, 2008
Contemporary U.S. federalism is a complex mixture of coercive, cooperative,and dual elements. Constitutionally and politically, the federal system hasbecome coercive because there has been a vast expansion of federal-governmentpower over the states since
John Kincaid
doaj  

Face mask uptake in the absence of mandates during the COVID-19 pandemic: a qualitative interview study with Swiss residents

open access: yesBMC Public Health, 2021
Background In the COVID-19 pandemic, Switzerland introduced broad nationwide face mask mandates only by October 2020, later than other Western European countries.
Bettina Maria Zimmermann   +3 more
doaj   +1 more source

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