Results 21 to 30 of about 2,058,759 (211)

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Improving High‐Temperature Operational Stability of Inverted Perovskite Solar Cells Through MXene Heat‐Dissipating Layers

Advanced Science, EarlyView.
MeO‐2PACz‐functionalized MXene nanosheets create a thermally conductive buried interface in inverted perovskite solar cells. The interface improves heat spreading, suppresses defects and ion migration, and strengthens charge extraction, extending T80 at 65°C from 141 to 687 h while maintaining competitive efficiency.
Masoud Karimipour, Nil Monrós Oliveras, Zhenchuan Tian, Timm Swoboda, Francesco Salutari, Marianna Sledzinska, Maria Chiara Spadaro, Kenedy Tabah Tanko, Javier Rodríguez‐Viejo, Jordi Arbiol, Tiankai Zhang, Feng Gao, Monica Lira‐Cantu   +12 more
wiley   +1 more source

Wearable E‐Textiles for Cardiovascular Monitoring: Materials, Devices, and Integrated Systems

Advanced Science, EarlyView.
The graphical abstract highlights the role of conductive materials and textile fabrication techniques in enabling smart textiles for cardiovascular applications. It showcases textile‐based ECG monitoring, pulse sensing, hemodynamic monitoring, and cardiovascular tissue engineering, while emphasizing the challenges and design considerations that govern ...
Bangul Khan, Mahmoud Tavakoli, Norbert Radacsi, Bee Luan KHOO   +3 more
wiley   +1 more source

An Expertise Transfer Framework For Autonomous Surgical Assistance

Advanced Science, EarlyView.
This study introduces an expertise transfer framework for procedure‐spanning autonomous surgical assistance. By emulating expert logic through hierarchical perception, attention modeling, and knowledge graph‐based decision‐making, the system provides near‐expert surgical view assistance.
Yuan Gao, Guangdi Chu, Wei Jiao, Yuchuan Zhong, Hang Yuan, Chengjun Li, Jinhua Li, Shuxin Wang, Bo Guan, Jianchang Zhao, Lizhi Pan, Haitao Niu, Jianmin Li   +12 more
wiley   +1 more source

Other title: Report on Federal Awards in Accordance with OMB Circular A-133 for the Year Ended June 30, 2005

, 2005
"Reissued."; application/pdf; "May 2012."; "A Report to the Legislative Post Audit Committee"--Cover."This report is a re-issue of the 2005 statewide OMB Circular A-133 federal compliance audit report.
Allen, Gibbs & Houlik.
core   +1 more source

Morphology‐Defined Entropy Streams for Random‐Bit Generation and Probabilistic Sampling in Memristor Arrays

Advanced Science, EarlyView.
Au nanoisland morphology defines stochastic high‐resistance‐state transport in Ag/TiO2 memristor arrays, transforming nanoscale structural disorder into a tunable physical entropy resource. Morphology‐controlled field hotspots and reset‐modulated nanogaps generate statistically validated random‐bit streams, which further serve as device‐derived ...
Hyunjun Kim, Da Ye Kim, Noah Jang, Yongho Lee, Byunghun Song, June Soo Kim   +5 more
wiley   +1 more source

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

Advanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo, Katie Shi, Lina Kafadarian, Alexandra Bermudez, Johnny Diaz, Liam Edwards, Yunqi Hong, Ziyi Chen, Hyeonji Hwang, Weihong Yan, Alan Levinson, Robert Damoiseaux, Cho‐Jui Hsieh, Tanya Stoyanova, Andrew S. Goldstein, Neil Y.C. Lin   +15 more
wiley   +1 more source

Mandatory audit firm rotation in Spain: a policy that was never applied [PDF]

In recent international debates on auditing regulation, Spain has assumed a real prominence as a claimed practical example of where a policy of mandatory audit firm rotation did not work and was duly abolished.
NIEVES CARRERA
core  

CausalCellInfer: Prioritizing Cell‐Type‐Specific Disease Associations From Genetically Predicted Transcriptomes in Biobank Cohorts

Advanced Science, EarlyView.
Bulk and genotype‐imputed transcriptomes obscure the cellular drivers of complex disease. CausalCellInfer resolves them by integrating invariant marker selection, deep learning deconvolution, and regularized matrix completion. Applied to ∼500 000 UK Biobank participants across 29 traits, it uncovers hallmark cell‐type proportion shifts, including ...
Liangying Yin, Yujia Shi, Ruoyu Zhang, Yong Xiang, Jinghong Qiu, Pak‐Chung Sham, Hon‐Cheong So   +6 more
wiley   +1 more source