Results 91 to 100 of about 6,844,914 (287)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Prerequisites of Formation of Strategy of the Food Market Development within Import Substitution and Resource-saving Programs (on the Example of St. Petersburg)

Управленческое консультирование, 2018
This study describes the necessity of strategy’s creation of the food market within the programs of import substitution and resource-saving program.Aim. Show the need to create a strategy for the food market within the programs of importsubstituting and ...
S. S. Voronkov
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Understanding the U.S. Generic Advertising System and its Role in Information Management among Commodities and Food Systems

International Journal on Food System Dynamics, 2010
 Information is essential to growing demand and maintaining efficiency throughout the supply chain for any commodity. The U.S. model for facilitating producers and first handlers having a proactive role in the flow of information about their ...
Ron W. Ward
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Methodological approaches for the prevention and eradication of caprine arthritis-encephalitis in international goat herds: A review

Ветеринария сегодня
Introduction. Caprine arthritis-encephalitis (CAE) is a chronic viral disease of goats caused by a lentivirus from the Retroviridae family (small ruminant lentivirus group, SRLV).
V. Yu. Koptev, N. O. Likhacheva, N. A. Shkil, I. M. Yurkova   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Growing Up in Quarantine: Exploring the Implications of Mandatory Social Isolation Due to COVID-19 on the Body Mass Index of Children and Adolescents

Iatreia
Introduction: Childhood obesity is a global health crisis. In Colombia, the implementation of the preventive mandatory social isolation during the COVID-19 pandemic led to the suspension of school programs, resulting in lifestyle changes in children and ...
Apraez, Karen, Moreno-Turriago, Mabel, Gutiérrez, Kenny, Soto-Aparicio, Maria José, Martínez-Betancur, Sofía, Sierra, Jimena Alexandra, Molina, María José, Rincón, Angie Lizeth, Lemus, Rodrigo, Angulo-Mosquera, Mario   +9 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source