Results 41 to 50 of about 90,375 (260)
Mandatory Public Health Programs: To What Standards Should They Be Held?
Health and Human Rights, 1999 Implicitly and explicitly, human rights have played a significant role in public health debates for decades. At the turn of the century, when health department officials in the United States were debating measures to control sexually transmitted diseases, it was argued that "the progress of preventive medicine has been a history of the conflict between
S J, Heymann, R L, Sell
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
USDA's Application of Administrative PAYGO to Its Mandatory Spending Programs [PDF]
, 2011 Correspondence issued by the Government Accountability Office with an abstract that begins "In fiscal year 2010, about 80 percent of the U.S. Department of Agriculture's (USDA) total outlays of about $129 billion was used to fund mandatory spending ...
United States. Government Accountability Office.
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Are welfare employment programs effective? [PDF]
Employment programs meant to place welfare adults in work or training became an important part of Aid to Families with Dependent Children starting in the 1980s.
L. M. Mead
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Mandatory Spending Since 1962 [PDF]
, 2010 Mandatory spending includes federal government spending on entitlement programs as well as other budget outlays controlled by laws other than appropriation acts.
Austin, D. A., Levit, Mindy R.
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source