Results 81 to 90 of about 406,257 (283)

Flexible RNA design under structure and sequence constraints using formal languages [PDF]

, 2013
The problem of RNA secondary structure design (also called inverse folding) is the following: given a target secondary structure, one aims to create a sequence that folds into, or is compatible with, a given structure.
Denise, Alain, Ponty, Yann, Vialette, Stéphane, Waldispühl, Jérôme, Zhang, Yi, Zhou, Yu   +5 more
core   +5 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The scalar spectrum of many-flavour QCD

, 2013
The LatKMI collaboration is studying systematically the dynamical properties of N_f = 4,8,12,16 SU(3) gauge theories using lattice simulations with (HISQ) staggered fermions.
Aoki, Yasumichi, Aoyama, Tatsumi, Kurachi, Masafumi, Maskawa, Toshihide, Nagai, Kei-ichi, Ohki, Hiroshi, Rinaldi, Enrico, Shibata, Akihiro, Yamawaki, Koichi, Yamazaki, Takeshi   +9 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Engineering the electrical and optical properties of graphene oxide via simultaneous alkali metal doping and thermal annealing

Journal of Materials Research and Technology, 2020
In order to extend the application of graphene oxide (GO) in the area of electronic industries, enhancing the electrical properties of GO as a cost-effective alternative for graphene seems mandatory.
Samira Naghdi, Hyun Yong Song, Alejandro Várez, Kyong Yop Rhee, Sung Wng Kim   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A Review on Temperature-Dependent Electrochemical Properties, Aging, and Performance of Lithium-Ion Cells

Batteries, 2020
Temperature heavily affects the behavior of any energy storage chemistries. In particular, lithium-ion batteries (LIBs) play a significant role in almost all storage application fields, including Electric Vehicles (EVs).
Mohammad Alipour, Carlos Ziebert, Fiorentino Valerio Conte, Riza Kizilel   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A Bayesian updating procedure for the electromechanical properties of piezoelectric energy harvesters

MATEC Web of Conferences, 2018
In the last decade, several numerical and analytic procedures have been proposed to predict the dynamic behavior of piezoelectric energy har- vesters (PEHs).
Peralta Patricio, Ruiz Rafael O., Meruane Viviana   +2 more
doaj   +1 more source