Results 171 to 180 of about 514,928 (277)

Should vaccination be mandated? Individuals' perceptions on mandatory vaccination in Greece. [PDF]

J Eval Clin Pract, 2021
Giannouchos TV, Steletou E, Saridi M, Souliotis K.   +3 more
europepmc   +1 more source

The question of mandatory vaccination and vaccination coverage

, 2016
The main concern of this thesis is the issue of mandatory vaccination and vaccination coverage in the Czech Republic. Therefore it focuses on all vaccines against infectious diseases which are now mandatory for all of the children: measles, mumps ...
Borovcová, Anna
core  

A Single‐Amino‐Acid Ligand for LAT1: A Minimalist and Modular Platform for Lysosome‐Targeted Degradation of Membrane Proteins

Advanced Science, EarlyView.
LA‐LYTAC repurposes the cancer‐enriched amino acid transporter LAT1 as a lysosomal trafficking receptor for targeted membrane‐protein degradation. A single phenylalanine‐derived ligand, modularly linked to antibodies or small‐molecule binders, recruits PD‐L1, EGFR, or integrins to LAT1, triggering transporter‐mediated internalization, lysosomal ...
Liquan Zhu, Ke Liu, Haotian Liu, Chaoqi He, Xiaozhen Liu, Xin Zeng, Misha Mao, Yuxiao Mu, Ying Li, Qinghui Zheng, Hongchao Tang, Da Qian, Xuli Meng   +12 more
wiley   +1 more source

Preparing for the Next Pandemic: A Cross-Sectional Study to Assess the Perspectives of Healthcare Staff and Patients on Mandatory Vaccination for Healthcare Workers in a National Health Service (NHS) Hospital Trust. [PDF]

Cureus
Rahemtoola MS, Pillai A.
europepmc   +1 more source

From a voluntary vaccination policy to mandatory vaccination against COVID-19 in cancer patients: an empirical and interdisciplinary study in bioethics. [PDF]

BMC Med Ethics, 2022
Stoeklé HC, Sekkate S, Angellier E, Kennel T, Benmaziane A, Mabro M, Geay JF, Beuzeboc P, Hervé C.   +8 more
europepmc   +1 more source

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

Advanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu, Kangkang Liu, Keruo Wang, Heyang Guan, Jiaming Fan, Taipeng Li, Jiaru Hao, Zeyuan Wang, Yongchao Yan, Jiatong Chen, Yuan Ma, Yang Yang, Yuanjie Niu   +12 more
wiley   +1 more source

How Public Health Professionals View Mandatory Vaccination in Italy-A Cross-Sectional Survey. [PDF]

Vaccines (Basel), 2021
Pitini E, Baccolini V, Rosso A, Massimi A, De Vito C, Marzuillo C, Villari P.   +6 more
europepmc   +1 more source

Comparability Effects of Mandatory IFRS Adoption [PDF]

The mandatory adoption of IFRS by many countries worldwide fuels the expectation that financial accounting information might become more comparable across countries.
Stefano Cascino, Joachim Gassen
core  

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

Advanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu, Jie Huang, Xiaojin Gao, Lin Deng, Yanheng Deng, Denglu Wang, Chunlei Yu, Yunxiang Zhang, Jingdong Li, Xiaocong Xiang   +9 more
wiley   +1 more source

Editorial Commentary on the paper "Mandatory vaccination in Europe". [PDF]

Transl Pediatr, 2020
Hadjipanayis A, Efstathiou E.
europepmc   +1 more source