Results 231 to 240 of about 35,398 (275)
Advanced Science, EarlyView.This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen +7 more
wiley +1 more source
Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening
Advanced Science, EarlyView.Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun +6 more
wiley +1 more source
The issue of mandatory vaccination for healthcare workers in Europe
Expert Review of Vaccines, 2014 Mandatory policies have occasionally been implemented, targeting optimal vaccination uptake among healthcare workers (HCWs). Herein, we analyze the existing recommendations in European countries and discuss the feasibility of implementing mandatory ...
Emmanouil Galanakis +2 more
exaly +2 more sources
Mandatory vaccination for infants and children: the Italian experience
Pathogens and Global Health, 2019 Maintaining high vaccination coverage is important in order to protect the individual and the community. Mandatory vaccination is an option in case of declining coverage. Widely used in the USA, it is considered a rather controversial issue in Europe. In
Giovanni Rezza
exaly +2 more sources
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The legality of mandatory vaccination
Indian Journal of Medical Ethics, 2019Vaccination in India has been carried out for the past 70 years and is seen as a major part of the public health policy of independent India. Its ability to provide for an efficient and cheap form of preventive healthcare makes it the most viable option for a developing state such as India.
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2021
Across the world, mass vaccination programs run by governments or third-sector organizations have saved countless lives; minimized human suffering; and maintained economic, social, and cultural functioning. Vaccination programs predominantly focus on diseases that once ravaged the infant and early childhood years.
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Across the world, mass vaccination programs run by governments or third-sector organizations have saved countless lives; minimized human suffering; and maintained economic, social, and cultural functioning. Vaccination programs predominantly focus on diseases that once ravaged the infant and early childhood years.
openaire +1 more source
The case for mandatory vaccination
Nature, 2019When immunization rates dip, legislation is often strengthened. But does the evidence stack up? When immunization rates dip, legislation is often strengthened. But does the evidence stack up?
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Mandatory vaccination: is it ethical?
Practice Nursing, 2021Mandatory – or compulsory – vaccinations are controversial, with some arguing that individuals should have the right to assert their personal decisions without state interference. The recent decision to make COVID-19 vaccination mandatory for frontline NHS workers in England, as well as those working in social care, has thrown the idea into the ...
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Should childhood vaccination be mandatory? No
BMJ, 2012Paul Offit (doi:10.1136/bmj.e2434) believes that mandatory vaccination is needed to protect vulnerable people from infection, but David Salisbury argues that there are more workable ways to ensure high ...
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