Results 41 to 50 of about 1,384 (208)

The Diagnosis That Arrived Decades Late: Living Without and Then With Myhre Syndrome

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MIM #139210) is a rare multisystem disorder first described in 1981, characterized by short stature, neurodevelopmental delay, joint contractures, and cardiopulmonary complications. Its molecular basis, recurrent pathogenic variants in SMAD4, was not discovered until 2011. This narrative is based on a review of medical records,
Abdallah F. Elias
wiley   +1 more source

Spectrum of Congenital Anomalies in Myhre Syndrome—Insights Into Effects Brought by Altered TGF‐β Signaling via Gain‐of‐Function Variants in SMAD4

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is a rare genetic disorder characterized by progressive multisystem involvement. Gain‐of‐function missense heterozygous variants affecting the Ile500 residue and Arg496 residue of the SMAD4 gene are implicated in this condition.
Kawmadi Gunawardena, Alessandro De Falco, Deborah Osio, Eleanor Sherlock, Emma Kivuva, Erina Sasaki, Francis H. Sansbury, Nayana Lahiri, Patricia Foley, Sahar Mansour, Shane McKee, Tazeen Ashraf, Nicola Brunetti‐Pierri, Usha Kini   +13 more
wiley   +1 more source

HUBUNGAN STATUS GIZI TERHADAP KESEJAJARAN GIGI ANTERIOR MANDIBULA BERDASARKAN PENGUKURAN LITTLE’S IRREGULARITY INDEX PADA SISWA SMPN 5 PADANG

Cakradonya Dental Journal, 2017
Maloklusi merupakan kelainan pada oklusi gigi yang menjadi masalah kesehatan masyarakat. Ketidaksejajaran gigi anterior mandibula merupakan maloklusi yang sering terjadi, hal ini akan mengakibatkan beberapa gangguan seperti kurang estetik, sulit ...
Catur Hadi Arief Dermawan, Aida Fitriana, Yustini Alioes   +2 more
doaj   +1 more source

Scalp electroacupuncture targeting trigeminal nerve activation alleviates post‐traumatic stress disorder–induced depression and neuroinflammation in mice

Animal Models and Experimental Medicine, EarlyView.
Scalp electroacupuncture (SA) through activation of the trigeminal pathway exerts anti‐inflammatory, antidepressant, and anxiolytic effects in an animal model of post‐traumatic stress disorder induced by single prolonged stress. This suggests that SA is involved in neuroinflammation and changes in brain‐derived neurotrophic factor protein through the ...
Bombi Lee, Yoongeun Kim, Hyungjun Kim, Dae‐Hyun Hahm   +3 more
wiley   +1 more source

Mental Foramenin Lokalizasyonun Radyografik Olarak Değerlendirilmesi

Cumhuriyet Dental Journal, 2011
Amaç: Mental foramenin yerinin tam olarak lokalize edilmesi alt çeneye uygulanan cerrahi operasyonlar açısından kritik bir öneme sahiptir. Lokalizasyonunun çeşitliliği özellikle implant cerrahisi gibi bazı operasyonlar sırasında komplikasyona sebep ...
Fatih Sari, Koray Ozer, M Kara, Omer Kirmali, Şeref Ezirganlı   +4 more
doaj  

Influência da prótese total mucossuportada na posição da cabeça da mandíbula em relação à fossa mandibular

Brazilian Dental Science, 2010
O objetivo neste trabalho foi visualizar possíveis alterações do posicionamento da ATM em pacientes desdentados que não usavam prótese total ou que a utilizavam apenas no arco superior.
Cláudia Villela Bin, Talyta de Souza Reis, Paula Carolina de Paiva Komori, Cleber Frigi Bissoli, Júlio Cezar de Melo Castilho, Tarcisio José de Arruda Paes Junior   +5 more
doaj   +1 more source

Establishment of a chronic aspiration pneumonia mouse model using oropharyngeal aspiration of food suspension

Animal Models and Experimental Medicine, EarlyView.
Four aspiration methods (UV, IN, IT, and OA) were compared, and OA was identified as the most effective delivery technique. A chronic aspiration pneumonia model was then established through repeated OA of food suspension or gastric contents. Integrated analyses, including micro‐CT, histopathology, cytokine profiling, and RNA sequencing, revealed ...
Qianwen Li, Fansen Lin, Hongzhi Gao, Yun Zhao, Yuqi Liu   +4 more
wiley   +1 more source

Finite element analysis of feeding in red and gray squirrels (Sciurus vulgaris and Sciurus carolinensis)

The Anatomical Record, EarlyView.
Abstract Invasive gray squirrels (Sciurus carolinensis) have replaced the native red squirrel (Sciurus vulgaris) across much of Great Britain over the last century. Several factors have been proposed to underlie this replacement, but here we investigated the potential for dietary competition in which gray squirrels have better feeding performance than ...
Philip G. Cox, Peter J. Watson
wiley   +1 more source

Hemimandibulektomi dengan Rekonstruksi Mandibula dan Fiksasi Intermaksila sebagai Penatalaksanaan Ameloblastoma Mandibula Sinistra

Majalah Kedokteran Gigi Indonesia, 2012
Latar belakang. Ameloblastoma adalah tumor odontogenik yang jarang terjadi. Walaupun jinak tetapi bersifat merusak dan mempunyai tingkat kekambuhan yang tinggi.
Indria Nehriasari, Maria G Widiastuti
doaj   +1 more source

Tooth eruption status and bite force determine dental microwear texture gradients in albino rats (Rattus norvegicus forma domestica)

The Anatomical Record, EarlyView.
Abstract Dental microwear texture analysis (DMTA) is widely applied for inferring diet in vertebrates. Besides diet and ingesta properties, factors like wear stage and bite force may affect microwear formation, potentially leading to tooth position‐specific microwear patterns.
Daniela E. Winkler, Isabelle Bernetière, Christine Böhmer   +2 more
wiley   +1 more source