Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard +3 more
wiley +1 more source
Precision of virtual surgical planning employing screw-holes locator and patient-specific implants versus conventional plate osteosynthesis for parasymphyseal mandibular fracture: a double-blinded randomized control trial. [PDF]
Abdellatif A +3 more
europepmc +1 more source
Zebrafish ventral gastrula fate map reveals neural crest progenitor domain
Abstract Background Fate maps relate progenitor cell positions to later fates and locations of their progeny, revealing early embryonic organization. Previous zebrafish fate maps identified the origin of germ layers and derivative cell fates, but ventral gastrula progenitor domains were not fully resolved. In particular, the neural crest, a multipotent
Elaine E. Kushkowski, Victoria E. Prince
wiley +1 more source
Patient-specific implants and virtual surgical planning in surgery-first orthognathic surgery: a case series and review of literature. [PDF]
Ananda N +4 more
europepmc +1 more source
Jaw‐specific stem cell dynamics are associated with distinct enamel architecture in mouse incisors
Abstract Background The continuously growing mouse incisor serves as a model for stem cell‐driven tooth renewal. Although mice possess maxillary and mandibular incisors, most studies have focused on the mandible. Potential differences in structure and renewal between these serially homologous organs remain insufficiently characterized.
Elias Shahin +4 more
wiley +1 more source
Comparative evaluation of total mandibular inferior border circumferential osteotomy and T-chinoplasty with mandibular angle osteotomy. [PDF]
Xiong J, Xu W, Wei M, He D.
europepmc +1 more source
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová +5 more
wiley +1 more source
Assessment of plan-execution fidelity in a fully digital workflow using custom-made plates for mandibular fracture repair: a prospective pilot study. [PDF]
Riad RK, Shalaby E, ElHawary H.
europepmc +1 more source
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini +2 more
wiley +1 more source
Morphological variations and differences of the mandible and midfacial skeleton across different sagittal skeletal patterns and sexes: a three-dimensional geometric morphometric analysis. [PDF]
Zhao G, Su X, He D, Gu Y.
europepmc +1 more source

