Results 41 to 50 of about 417 (147)

Gene Therapy Using Recombinant AAV Type 8 Vector Encoding TNAP‐D10 Improves the Skeletal Phenotypes in Murine Models of Osteomalacia

open access: yesJBMR Plus, Volume 7, Issue 1, January 2023., 2023
ABSTRACT Hypophosphatasia (HPP), caused by loss‐of‐function mutations in the ALPL gene encoding tissue‐nonspecific alkaline phosphatase (TNAP), is characterized by skeletal and dental hypomineralization that can vary in severity from life‐threatening to milder manifestations only in adulthood.
Flavia Amadeu de Oliveira   +7 more
wiley   +1 more source

Total mandible and bilateral TMJ reconstruction combining a customized jaw implant with a free fibular flap: a case report and literature review

open access: yesMaxillofacial Plastic and Reconstructive Surgery, 2023
Background The need for whole mandibular bone reconstruction and bilateral joint replacement is fortunately rare, but it is an extremely challenging topic in maxillofacial surgery, due to its functional implications.
Flavio Andrea Govoni   +6 more
doaj   +1 more source

Root and root canal morphology of permanent mandibular first and second molars in a Kuwaiti population: A retrospective cone-beam computed tomography study

open access: yesSaudi Dental Journal, 2023
Aim: Endodontic diseases typically affect the mandibular molars. Understanding the complex morphology of the root canal system and its variations is necessary for successful endodontic treatment.
Humoud S. Alazemi   +2 more
doaj  

Functional Analyses of SATB2 Variants Reveal Pathogenicity Mechanisms Linked With SATB2‐Associated Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT SATB2‐associated syndrome (SAS) is characterized by intellectual disability, neurodevelopmental disorders, cleft palate, and dental abnormalities. SAS is caused by variants in the special AT‐rich sequence‐binding protein 2 (SATB2), which encodes a transcription factor containing two CUT domains and a homeobox (HOX) domain.
Nao Ukita   +5 more
wiley   +1 more source

Elucidating the Molecular Landscape of Cystic Kidney Disease: Old Friends, New Friends and Some Surprises

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cystic kidney diseases (CyKD) are a diverse group of disorders affecting more than 1 in 1000 individuals. Over 120 genes are implicated, primarily encoding components of the primary cilium, transcription factors, and morphogens. Prognosis varies greatly by molecular diagnosis. Causal variants are not identified in 10%–60% of individuals due to
Deborah Watson   +10 more
wiley   +1 more source

Evaluation of mandibular condyles in children with unilateral posterior crossbite

open access: yesBrazilian Oral Research, 2015
The relationship of mandibular condyle dimensions and its association with unilateral posterior crossbite (UPXB) has been suggested in the literature. The purpose of this prospective study was to evaluate mandibular condyles on the left and right sides ...
Edson ILLIPRONTI-FILHO   +2 more
doaj   +1 more source

Efficacy of biologics for alveolar ridge preservation/reconstruction and implant site development: An American Academy of Periodontology best evidence systematic review

open access: yesJournal of Periodontology, Volume 93, Issue 12, Page 1827-1847, December 2022., 2022
Abstract Background The use of biologics may be indicated for alveolar ridge preservation (ARP) and reconstruction (ARR), and implant site development (ISD). The present systematic review aimed to analyze the effect of autologous blood‐derived products (ABPs), enamel matrix derivative (EMD), recombinant human platelet‐derived growth factor‐BB (rhPDGF ...
Fernando Suárez‐López del Amo   +1 more
wiley   +1 more source

Giant Cell Lesion or Langerhans' Cell Histiocytosis of the Mandible? A Case Report

open access: yesEuropean Journal of Inflammation, 2012
Langerhans' cell histiocytosis (LCH), formerly known as histiocytosis X, is characterized by cell proliferation. The leading clinical symptom of LCH within mandibular and maxillary bones is pain and it may resemble periodontal diseases, apical cysts ...
V. Valentini   +6 more
doaj   +1 more source

EFFECTS OF PAMIDRONATE ADMINISTRATION ON TOOTH ERUPTION AND MANDIBULAR GROWTH IN NEW BORN RATS

open access: yesJournal of Istanbul University Faculty of Dentistry, 2017
Purpose: Bisphosphonates are commonly used drugs in pediatric patients in the treatment of osteoporotic diseases and various types of cancers. The purpose of this study was to evaluate the effects of pamidronate administration on mandibular growth and ...
İbrahim Tuncer   +5 more
doaj   +1 more source

Co-Occurence of Florid Cemento-Osseous Dysplasia and Simple Bone Cyst: a Case Report

open access: yeseJournal of Oral Maxillofacial Research, 2011
Background: The purpose of this report is to present a rare case of co-occurrence of florid cemento-osseous dysplasia with simple bone cyst in a middle aged Asian woman.
Kumuda Arvind Rao   +3 more
doaj  

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