Results 121 to 130 of about 14,531 (351)
TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2
Advanced Science, EarlyView.This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao +12 more
wiley +1 more source
Fracture and Structural Integrity, 2018 . This paper presents a numerical investigation about the influence of mandrel shape on residual stresses induced by the cold expansion procedure. Thus, ball and tapered pin are used for cold expanding the plate. As, the entrance face presents the lowest
Abdelghani BALTACH +4 more
doaj
Advanced Energy Materials, EarlyView.This study investigates the feasibility of scaling up Prussian White (PW)‐based cathode manufacturing at a pilot scale. Through careful PW dehydration combined with optimized aqueous processing, we report the stepwise development of industrially relevant 1 Ah pouch cells and evaluate their performance under various conditions.
Faduma M. Maddar +7 more
wiley +1 more source
Advanced Intelligent Systems, EarlyView.This paper presents a degeneracy‐aware light detection and ranging (LiDAR)‐inertial framework that enhances LiDAR simultaneous localization and mapping performance in challenging environments. The proposed system integrates a dual‐layer robust odometry frontend with a Scan‐Context‐based loop‐closure detection backend.
Haoming Yang +4 more
wiley +1 more source
American Journal of Botany, EarlyView.Abstract Premise Species of Deuterocohnia (17 spp.) show extraordinary variation in elevation (0–3900 m a.s.l.) and growth forms, and many have narrow geographic distributions in the west‐central Andes and the Peru‐Chile coast. Previous research using few plastid and nuclear loci failed to produce well‐resolved or supported phylogenies.
Bing Li +5 more
wiley +1 more source
American Journal of Community Psychology, EarlyView.Abstract Despite the heightened mental health challenges amid rising Anti‐Asian sentiment, Asian Americans have significantly underutilized mental health services, a trend that persisted even before the COVID‐19 pandemic. Although considerable efforts have been made to understand how various factors are related to mental health service use in this ...
Michael Park +6 more
wiley +1 more source
Teshugang, 2006 The 8- stand floating mandrel continuous rolling process of Φ169 mm x6 mm T91 steel seamless tube has been simulated and analyzed by 3- dimensional thermo-mechanical coupled FEM to get distribution of equivalent stress of across section at exit of each ...
洪慧平 +5 more
doaj
Harnessing the Neurobiology of Empathy and Compassion to Alleviate Burnout in Neurology
Annals of Neurology, EarlyView.The neurologist cares for patients with complex chronic conditions that compromise their wellbeing. Many such disorders are poorly understood. Whereas for some, effective symptomatic treatments exist, for most we lack an understanding of the molecular and cellular bases for disease pathogenesis needed for discovering disease‐modifying treatments ...
Fadel Zeidan +2 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective De novo mutations in the syntaxin‐binding protein 1 (STXBP1), encoded by STXBP1, are among the most prevalent causes of variable neurodevelopmental disorders, including epileptic encephalopathy, developmental delay, and movement disorders.
Tao Yang +7 more
wiley +1 more source