Results 31 to 40 of about 126,490 (263)

ON THE MANGANESE FERROCYANIDES. [PDF]

Journal of the American Chemical Society, 1902
n ...
openaire   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Catalytic enantioselective intramolecular hydroamination of alkenes using chiral aprotic cyclic urea ligand on manganese (II)

Nature Communications
Asymmetric catalysis for enantioselective intramolecular hydroamination of alkenes is a critical method in the construction of enantioenriched nitrogen-containing rings, often prevalent in biologically active compounds and natural products.
Bin Cui, Yuting Zheng, Hui Sun, Huijian Shang, Man Du, Yuxuan Shang, Cafer T. Yavuz   +6 more
doaj   +1 more source

Identification of Manganese Ore and Manganese Smelting Slag by X-ray Fluorescence Spectrometry, X-ray Diffraction and Fourier Transform Infrared Spectroscopy

Yankuang ceshi, 2015
It is very important to identify manganese ore and manganese smelting slag for manganese ore import trade and environmental protection. Due to the similarity of elements in manganese smelting slag and some manganese ore, such as Mn, Si, Al, Mg, Ca and ...
WU Su-ru, SONG Yi, GU Song-hai, GUO Fen, SUN Xin   +4 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Nano-hollow carbon-supported high-entropy alloy catalysts for energy-saving seawater electrolysis

Nano Research Energy
Electrolyzing seawater to produce hydrogen can not only address the issue of freshwater scarcity but also provide an abundant raw material for hydrogen production.
Quan Zhang, Zhiwei Wang, Lehua Wang, Zongchen Wei, Longchao Zhuo, Yifan Liu, Imran Shakir, Guangzhi Hu, Xijun Liu   +8 more
doaj   +1 more source

MANGANESE TOXICOSIS [PDF]

JAMA: The Journal of the American Medical Association, 1913
n ...
openaire   +2 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Manganese Oxidation State Assignment for Manganese Catalase [PDF]

Journal of the American Chemical Society, 2016
The oxidation state assignment of the manganese ions present in the superoxidized manganese (III/IV) catalase active site is determined by comparing experimental and broken symmetry density functional theory calculated (14)N, (17)O, and (1)H hyperfine couplings.
Beal, Nathan, O'Malley, Patrick
openaire   +3 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source