Results 141 to 150 of about 26,797 (254)

Bio‐Derived Carbon Nanoparticles: A Green Amendment for Alleviating Heavy Metals in Soil–Plant Systems

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT Heavy metal (HM) contamination of soil–plant systems poses persistent ecological and health risks, driving interest in nanoparticle‐based remediation. Although conventional chemically synthesized nanoparticles (CSNPs) are effective, their energy‐intensive production and residual toxicity limit sustainable deployment.
Babar Hussain   +6 more
wiley   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

Brassinin Inhibits Cell Survival and Autophagy via Modulation of ROS Production and the AMPKα‐beclin1 Signaling Pathway in Gliomas

open access: yesPhytotherapy Research, EarlyView.
Brassinin, a phytoalexin derived primarily from Chinese cabbage, exhibits potent anticancer activity against glioblastoma (GBM). Mechanistically, brassinin treatment elevates intracellular ROS levels in GBM cells, triggering two parallel outcomes: (i) direct induction of apoptosis, and (ii) suppression of cytoprotective autophagy through downregulation
Sunil Rauniyar   +7 more
wiley   +1 more source

Melittin Reprograms Tumor‐Associated Macrophages Through CD18‐Mediated Immunomodulation

open access: yesPhytotherapy Research, EarlyView.
Melittin selectively targets CD18 to deplete M2‐TAMs and remodel the TME to suppress tumor growth. ABSTRACT Tumor‐associated macrophages (TAMs), particularly the M2‐like subtype, contribute to an immunosuppressive tumor microenvironment and promote tumor progression.
Ik‐Hwan Han   +6 more
wiley   +1 more source

Nanopore and Self‐Assembled Monolayer Engineering of l‐Lactate Oxidase Gold Electrodes for Enhanced l‐Lactate Biosensing

open access: yesSmall, EarlyView.
A tiered nanoporous gold biointerface enables site‐directed immobilization of His‐tagged lactate oxidase through a mixed self‐assembled monolayer, achieving high enzyme loading while preserving activity. The resulting bioelectrode provides sensitive and stable l‐lactate detection (0.12–3.0 mM, 75 µA mM−1 cm−2), demonstrating a modular strategy for high‐
Mislav Sušac   +6 more
wiley   +1 more source

Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms

open access: yesThe Chemical Record, EarlyView.
Additive manufacturing enables the rational design of structured antimicrobial platforms across multiple length scales, from nanofibrous scaffolds and droplet microreactors to 3D and 4D printed constructs. By engineering confinement, interfacial chemistry, and stimuli‐responsive release, these systems exert localized action through complementary ...
Giorgia Puleo   +11 more
wiley   +1 more source

Oxidative Stress Biomarkers in the Shrimp Macrobrachium amazonicum (Heller, 1862): Assessment in an Environmental Preservation Area in the Brazilian Amazon

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Anthropogenic activities generate a significant amount of pollutants that are released into the environment, causing physiological and ecological disturbances. Among the xenobiotics present in aquatic ecosystems, numerous chemical and organic compounds have oxidative potential or are metabolized through oxidative processes, which may amplify ...
Natália Eduarda da Silva   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy