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Manganese poisoning and the attack of trivalent manganese upon catecholamines
Archives of Biochemistry and Biophysics, 1987Human manganese poisoning or manganism results in damage to the substantia nigra of the brain stem, a drop in the level of the inhibitory neurotransmitter dopamine, and symptoms resembling those of Parkinson's disease. Manganic (Mn3+) manganese ions were shown to be readily produced by O-2 in vitro and spontaneously under conditions obtainable in the ...
Frederick Archibald, Curtis M. Tyree
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Manganese poisoning: Clinical and biochemical observations
Environmental Research, 1974Abstract Clinical and biochemical studies were conducted in twelve cases of suspected manganese poisoning. On the basis of neurological observations they were divided into three grades of poisoning, mild, moderate and severe. A significant increase in serum calcium and adenosine deaminase levels was observed in cases of mild and moderate grades of ...
Satya V. Chandra +2 more
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Acta Neuropathologica, 1986
An autopsy case of a 52-year-old man suffering from chronic manganese poisoning (CMP) is reported with determination of the manganese distribution in the brain. The patient had been working in a manganese ore crushing plant since 1965. In 1967 he began to complain of difficulties in walking and diminished libido.
Hiroshi Tsukagoshi +7 more
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An autopsy case of a 52-year-old man suffering from chronic manganese poisoning (CMP) is reported with determination of the manganese distribution in the brain. The patient had been working in a manganese ore crushing plant since 1965. In 1967 he began to complain of difficulties in walking and diminished libido.
Hiroshi Tsukagoshi +7 more
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Neurology, 1968 Internationales Archiv f�r Arbeitsmedizin, 1971
In 46 persons among 119 workers at a foundry producing manganese alloy, manganese levels of over 20 µg% were found in the blood without marked objective symptoms of manganese poisoning. Comparison with a control group showed differences in magnesium and calcium levels, AlAT, AspAT, LDH, LAP activities, albumin, α1- and Β-globulin, bilirubin ...
G. Jonderko +2 more
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In 46 persons among 119 workers at a foundry producing manganese alloy, manganese levels of over 20 µg% were found in the blood without marked objective symptoms of manganese poisoning. Comparison with a control group showed differences in magnesium and calcium levels, AlAT, AspAT, LDH, LAP activities, albumin, α1- and Β-globulin, bilirubin ...
G. Jonderko +2 more
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[Effects of polygala on the neurogenesis of manganese poisoned mice].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2015To investigate the effects of polygala on leaning and memory and the expression of Microtubule associated protein on manganese poisoned mice.60 female Kunming mice were randomly and equally divided into 5 group. They are normal control group (CG), manganese poisoned group (MG), manganese poisoned with polygala high dose group (MHG), manganese poisoned ...
Xuechao Jing, Boning Yang, Li Qin
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Psychiatric illness due to manganese poisoning
Acta Psychiatrica Scandinavica, 1983Rats were exposed to manganese (1 mg/ml through drinking water) daily to study behavioral and neurochemical changes 14 and 30 days after the treatment. Manganese produced hyperactivation after 14 and 30 days with greater magnitude of alteration at the latter period.
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Myoclonic involuntary movement associated with chronic manganese poisoning
Journal of the Neurological Sciences, 2002We report a 17-year-old man showing myoclonic involuntary movement (IVM) associated with chronic manganese (Mn) poisoning. The patient, a welder, showed myoclonic IVM mainly in the right upper and lower extremities, elevated levels of Mn in the blood and hair and high-intensity signals in the globus pallidus on T1-weighted MR images.
Masahito Yamada +2 more
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[Investigation on occupational manganese poisoning hazard in Guang Xi].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2009目的 调查职业性锰接触的危害程度和工人健康状况,为职业病防治和监督管理工作提供科学依据.方法 对广西2家大型锰矿生产及锰冶炼厂进行现场卫生学调查、职业病危害因素检测和作业人员职业健康检查并进行5年历史性队列研究.结果 近30年锰作业场所空气中二氧化锰平均浓度为0.45 mg/m3;2007年锰累积暴露指数(年空气锰平均浓度与作业工龄加权值,CEI)的平均值为5.77 mg·m-3年.近5年接触者的尿锰平均水平无增高趋势,锰作业观察对象和疑似慢性锰中毒者有增多迹象;尿锰、慢性锰中毒诊断情况与CEI呈正相关.结论 CEI能反映慢性锰中毒严重情况,是较好的评价锰的累积暴露剂量的指标。
You-rong Lu, Yan-ning Li, Hou-jian Li
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