Results 121 to 130 of about 59,324 (254)

Ketogenic Diet Alleviates Colorectal Cancer by Attenuating Macrophage M2 Polarisation Triggered by Oncometabolite MMA Derived From the Gut Microbiota

Cell Proliferation, EarlyView.
Proposed mechanism of the ketogenic diet‐microbiota‐MMA‐immune axis in CRC. (Part 1) A ketogenic diet remodels gut microbiota homeostasis by depleting MMA‐producing bacteria, thereby reducing the accumulation of the oncometabolite (MMA). (Part 2) At the molecular level, MMA acts as a ligand that binds to Rap1, activating the downstream MAPK/ERK ...
Yang Lu, Bo Shi, Jinmiao Chen, Huihui Yao, Xiuwei Mi, Minke Shao, Yiyuan Zhao, Lijun Meng, Qingliang Tai, Junjie Chen, Xinyu Shi, Diyuan Zhou, Yizhou Yao, Songbing He   +13 more
wiley   +1 more source

Correction: Epidemiology of cardiovascular disease and diabetes in 2026: expanding prevalence, escalating costs, and the limits of contemporary prevention. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Santulli G.
europepmc   +1 more source

The aesthetic sublime of megaproject structures: A framework and a research agenda

European Management Review, EarlyView.
Abstract The physical structures of megaprojects—such as mega‐canals, metros, railway lines, bridges, tunnels, and iconic opera houses—hold a profound capacity to generate aesthetic experiences with enduring societal impact. Yet, research on megaprojects has predominantly focused on functionality and economic rationale with aesthetics being pushed to ...
Federica De Molli, Alfons van Marrewijk, Arne Carlsen   +2 more
wiley   +1 more source

Generation of an Etiology Index Based on Confirmed Tissue Diagnosis Data to Assess Endemic Swine Etiology Activity in the United States of America. [PDF]

Transbound Emerg Dis
Cezar GA, Zhang D, Main RG, Burrough ER, Nicolino RR, da Costa MR, Silva G, Linhares DCL, Trevisan G.   +8 more
europepmc   +1 more source

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

The FEBS Journal, EarlyView.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture, Devi Nandana, Karthik Ramasamy, Anjan Thakurta   +3 more
wiley   +1 more source

Simulation-Guided Interpretable Fault Diagnosis of Hydraulic Directional Control Valves Under Limited Fault Data Conditions. [PDF]

Sensors (Basel)
Xia Y, Xiao A, Xiao H, Zhao X, Liu H.
europepmc   +1 more source

Reputation and Asset Prices: Evidence From Trump Real Estate

Financial Management, EarlyView.
ABSTRACT We analyze the impact of brand reputation on asset prices by exploiting the prominence of Donald Trump in Manhattan real estate. Our quasi‐experiment identifies a 14.5% discount to condominiums in Trump‐branded buildings after controversies surrounding Trump's presidential candidacy began in June 2015 up to 2022.
Marlene Koch, Simon Stehle, Rémi Vivès
wiley   +1 more source

Whole Genome Sequence Analysis of Weight Loss in 16 972 Participants With COPD Reveals Novel Risk Loci in DRAIC and RFX3. [PDF]

J Cachexia Sarcopenia Muscle
Chiles JW, Rocco A, Srinivasasainagendra V, Rossiter HB, Casaburi R, Thalacker-Mercer A, Wells JM, Wan ES, Silverman EK, Cho MH, Hersh CP, Psaty BM, Gharib SA, Gao Y, O'Connor GT, Lange LA, Rich SS, Manichaikul AW, Barr RG, Ortega VE, Meyers DA, Smith AV, Tiwari HK, McDonald MN.   +23 more
europepmc   +1 more source

Housing Wealth and Consumption: The Role of Heterogeneous Credit Constraints

International Economic Review, EarlyView.
ABSTRACT We quantify the role of heterogeneity in households' financial constraints in explaining the link between the decline in aggregate consumption and the decline in house values between 2006 and 2009 using individual‐level data. Constraints that are triggered by a decline in house values, and a small fraction of consumers facing particularly ...
S. Borağan Aruoba, Ronel Elul, Şebnem Kalemli‐Özcan   +2 more
wiley   +1 more source

Salesmen of science: A textual analysis of technological advancement and quantum physics in <i>Oppenheimer</i> (2023). [PDF]

Public Underst Sci
Gustafson E.
europepmc   +1 more source