Results 131 to 140 of about 21,099 (238)

Multi‐Trait Genetic Insights Into Schizophrenia Across Ancestries: Genome‐Wide Association Meta‐Analyses, Machine Learning, and Drug Repurposing Study

open access: yesBrain and Behavior, Volume 16, Issue 7, July 2026.
ABSTRACT Background Schizophrenia is a psychiatric disorder characterized by a wide range of symptoms and a complex interplay between genetic and environmental factors. Despite advances in genomics, the genetic underpinnings of SC and its relationship with drug use remain poorly understood.
Ping Yan   +5 more
wiley   +1 more source

Exploring Genetic Contributions to Prostate Cancer Risk in an Asian Population‐Based Study

open access: yesCancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background Genetic susceptibility to prostate cancer (PCa) varies across populations, yet East Asian men remain underrepresented in genome‐wide association studies (GWAS). This study aimed to identify genetic variants associated with PCa in a Taiwanese cohort and to explore their potential biological relevance using integrative annotation ...
Jiun‐Hung Geng   +8 more
wiley   +1 more source

Evaluation of disease resistance in intermediate wheatgrass and genome‐wide association for fusarium head blight‐related traits

open access: yesCrop Science, Volume 66, Issue 4, July/August 2026.
Abstract Intermediate wheatgrass (IWG) [Thinopyrum intermedium (Host) Barkworth & D. R. Dewey] is a promising perennial grain candidate that The Land Institute has been directly domesticating since 2001. Grain from improved IWG can be sold under the trademark Kernza.
Leah K. Treffer   +4 more
wiley   +1 more source

Precision medicine for atherosclerotic cardiovascular disease: Integrative genomics maps risk loci and AI‐predicted functional consequences

open access: yesClinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Genomic SEM of five ASCVD traits in > 3.8 million individuals identified 347 risk variants, including 19 novel loci. Integrating fine‐mapping and TWAS prioritized causal genes and revealed endothelial cell enrichment in vascular tissues. AI modelling shows the DCLRE1B mutation destabilizes the protein, impairing DNA repair and transcription.
Liwan Fu   +4 more
wiley   +1 more source

Polygenic Risk Scores for Incident Dementia in the Multi‐Ethnic Study of Atherosclerosis

open access: yesGenetic Epidemiology, Volume 50, Issue 5, July 2026.
ABSTRACT Over 75 Alzheimer's disease (AD) and dementia‐associated variants have been identified through genome‐wide association studies, but the utility of polygenic risk scores (PRS) for predicting AD and dementia in diverse and admixed populations remains unclear.
Diane Xue   +6 more
wiley   +1 more source

Health Preferences and Sorting in the City

open access: yesHealth Economics, Volume 35, Issue 7, Page 1033-1055, July 2026.
ABSTRACT There are large health inequalities between neighborhoods in many cities of the world. This paper studies individuals' sorting based on health amenities and exposes an important connection between health preferences and the housing market. I estimate a neighborhood choice model using geolocated data from a health survey in New York City and ...
Manuela Puente‐Beccar
wiley   +1 more source

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