Results 31 to 40 of about 442,861 (243)

Research progress on symptom cluster management of lymphoma patients

Huli yanjiu, 2020
This article reviewed the research progress on symptom cluster management of lymphoma patients from the manifestations，evaluation tools，and intervention status of lymphoma patients，and intended to provide references for clinical evaluation and ...
CUI Panpan, TANG Han, GAO Xinyi, CHEN Changying   +3 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Manifestasi Behçet Disease yang Parah dan Komplikasi Perawatannya dalam Rongga Mulut

Journal of Dentistry Indonesia, 2013
Behçet’s Disease (BD) is a multisystem inflammatory disorder characterized by recurrent oral-genital ulcers, ocular inflammation and frequently involves the joints, skin, central nervous system and gastrointestinal tract.
Liza Meutia Sari, Titiek Setyawati
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Clinical manifestation and microbial profiling of recurrent MDR microorganisms associated with head and neck infection- a retrospective study

Healthcare in Low-resource Settings, 2023
Head and neck infection (HNI) can lead to life-threatening complications, including death. The purpose of this study is to look at the entire clinico-demographic profile of patients with HNI as well as the microbiologic profile of recurring bacterial ...
Smarita Lenka, Debasmita Dubey, Shakti Rath, Somadatta Das, Santosh Kumar Swain   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

An Assessment of the Views of Some Muslim Philosophers to Emanation or Making [PDF]

حکمت و فلسفه, 2012
The present article is an attempt to assess the views of those philosophers who are the exponents or founders of a particular school of thought on emanation or making. In the beginning, it seems that we can generally divide the philosophers only into two
monireh palangi
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Kutsalın Futboldaki Tezahürleri

Fırat Üniversitesi İlahiyat Fakültesi Dergisi, 2022
Tarih boyunca futbol oynandığı her dönemde toplumları etkileyen önemli bir rekabet ve görsel şölen olmuştur. Başlangıçta askeri talim ve üst düzey sınıfı eğlendirmek amacıyla ortaya çıkan futbol, zamanla kurumsallaşma açısından önemli bir ilerleme ...
Ali Albayrak, Salih Emre Karayel
doaj