Results 71 to 80 of about 1,173,149 (341)

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Conservative management of low back pain [PDF]

, 2001
Back pain is prevalent worldwide, but back pain disability has reached epidemic proportions in many industrialised societies. Few patients have serious medical pathology or direct neurological involvement requiring surgery.
De Souza, LH, Frank, AO
core  

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

Analysis of kinematic and kinetic changes in scoliosis following spinal manipulation

Scientific Reports
Scoliosis is a prevalent condition among adolescents, and the spinal manipulation is one of the conservative treatment methods for scoliosis patients. Impairment in movement function stands out as a typical characteristic in cases of scoliosis.
Yanyun Gou, Lin Meng, Shaoqing Chen, Zheng Jiang, Huangwei Lei   +4 more
doaj   +1 more source

Global Burden Related to Nitrous Oxide Exposure in Medical and Recreational Settings: A Systematic Review and Individual Patient Data Meta-Analysis. [PDF]

, 2019
The risk of adverse effects of nitrous oxide (N2O) exposure is insufficiently recognized despite its widespread use. These effects are mainly reported through case reports. We conducted an individual patient data meta-analysis to assess the prevalence of
Filhine-Tresarrieu, Pierre, Franczak, Claire, Green, Ralph, Guéant, Jean-Louis, Hajjar, Olivia, Julien, Mélissa, Laugel, Elodie, Levy, Julien, Oussalah, Abderrahim, Stephan, Charlotte, Wandzel, Marion   +10 more
core   +3 more sources

Clinical Scenarios for Which Spinal Mobilization and Manipulation Are Considered by an Expert Panel to be Inappropriate (and Appropriate) for Patients With Chronic Low Back Pain

Medical Care, 2019
Background: Spinal mobilization and manipulation are 2 therapies found to be generally safe and effective for chronic low back pain (CLBP). However, the question remains whether they are appropriate for all CLBP patients. Research Design: An expert panel
P. Herman, E. Hurwitz, P. Shekelle, Margaret D. Whitley, I. Coulter   +4 more
semanticscholar   +1 more source

Biobased Bionic Spider Silk via Electrostatic Complexation for Simultaneously Harvesting Atmospheric Water and Triboelectric Energy

Advanced Functional Materials, EarlyView.
Bio‐based bionic spider silk and spider web are first prepared using polyelectrolyte complexation technique for the simultaneous harvesting of water and triboelectric energy. The advantage of this process lies on entirely bio‐based materials, fully green water‐processable procedures, extremely high production rate (99.36%), excellent fog harvesting ...
Qin Chen, Araz Rajabi‐Abhari, Tongtong Fu, Haonan Zhang, Siqi Huan, Liang Chen, Jinchao Li, Cheng Hao, Yaping Zhang, Ning Yan   +9 more
wiley   +1 more source

Clinical and surgical management of holocervical spinal cord ependymomas. [PDF]

, 2019
Background:Spinal ependymomas are rare tumors of the central nervous system, and those spanning the entire cervical spine are atypical. Here, we present two unusual cases of holocervical (C1-C7) spinal ependymomas.
Attiah, Mark, Batzdorf, Ulrich, Churchman, Pedro, Gaonkar, Bilwaj, Macyszyn, Luke, Mckay, Kevin, Moreland, Natalie, Nagasawa, Daniel, Niu, Tianyi, Patel, Kunal, Tucker, Alexander, Van de Wiele, Barbara   +11 more
core  

Spin‐Dependent Generation of Surface‐Bound Radicals Toward Selective and Long‐Lasting Water Purification

Advanced Functional Materials, EarlyView.
This study develops a novel atomic engineering strategy to fine‐tune the spin state of α‐Fe2O3 catalysts toward a medium‐spin state, thereby modulating peroxymonosulfate activation and selectively yielding surface‐bound radicals. Compared with free radicals, surface‐bound radicals exhibit moderated oxidation potential, extended lifespan, surface ...
Shuyu Wang, Zhonglin Chen, Jimin Shen, Pengwei Yan, Jing Kang, Binyuan Wang, Shengxin Zhao, Xiaoguang Duan   +7 more
wiley   +1 more source

Free-View, 3D Gaze-Guided, Assistive Robotic System for Activities of Daily Living [PDF]

, 2018
Patients suffering from quadriplegia have limited body motion which prevents them from performing daily activities. We have developed an assistive robotic system with an intuitive free-view gaze interface.
Darzi, Ara, Kogkas, Alexandros A., Mylonas, George P., Wang, Ming-Yao   +3 more
core   +2 more sources