Results 201 to 210 of about 505,478 (275)

Arthroscopic Anterior Cruciate Ligament Repair With Suture Augmentation Provides Good to Excellent Midterm Functional Outcomes Despite Clinically Relevant Revision Rates

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate midterm functional outcomes after anterior cruciate ligament (ACL) repair with suture augmentation and to determine whether concomitant injuries influence patient‐reported outcomes. Methods This retrospective single‐center cohort study included patients undergoing arthroscopic ACL repair with suture augmentation between January 2017
Anna Patricia Egert   +6 more
wiley   +1 more source

CASTOR1 Regulates Humoral Immune Responses and Contributes to the Pathogenesis of Systemic Lupus Erythematosus

open access: yesArthritis &Rheumatology, EarlyView.
Objective CASTOR1 senses arginine and regulates mammalian target of rapamycin complex 1 (mTORC1), a central metabolic signaling molecule. This study aimed to elucidate the roles of CASTOR1 in humoral immune responses. Methods We analyzed human B cell transcriptomes from healthy controls and patients with systemic lupus erythematosus (SLE) via ...
Takeshi Kusuda   +5 more
wiley   +1 more source

Hepatitis C virus can induce gene expression changes associated with hepatocarcinogenesis. [PDF]

open access: yesJHEP Rep
Boldanova T   +8 more
europepmc   +1 more source

A Study On Faster Mann Iterative Method

open access: yesAfyon Kocatepe University Journal of Sciences and Engineering, 2018
openaire   +1 more source

Persistent Interleukin‐18 Fuels Expansion of CD38+HLA‐DR+CD8+ T Cells in Still Disease and Macrophage Activation Syndrome

open access: yesArthritis &Rheumatology, EarlyView.
Objective Still disease (SD) is an autoinflammatory disorder characterized by remarkably high interleukin‐18 (IL‐18) levels. Increasing evidence suggests that adaptive immunity also contributes to its pathogenesis, particularly in refractory courses. Macrophage activation syndrome (MAS), one of SD's most severe complications, is associated with further
Greta Rogani   +17 more
wiley   +1 more source

The synergistic impact of granulocytic myeloid‐derived suppressor cells and innate lymphoid cells in systemic sclerosis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Systemic sclerosis (SSc) is a chronic autoimmune disorder characterized by immune dysregulation and fibrosis, with myeloid‐derived suppressor cells (MDSCs) emerging as important regulators of immune responses. However, the role of MDSCs in SSc‐associated fibrosis and their interactions with other immune cell populations remain poorly ...
Stefanie Weber   +15 more
wiley   +1 more source

Sema4A neutralization reduces fibrosis and inflammation in a mouse model of systemic sclerosis and a 3D model of immunity‐driven fibrosis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective We previously showed that Semaphorin4A (Sema4A) is elevated in patients with systemic sclerosis (SSc) and promotes inflammation and fibrosis in vitro. Here, we examined the effect of Sema4A neutralization in vivo and in 3D fibrosis models. Methods Sema4A plasma levels were measured by ELISA in healthy controls (n=31) and patients with SSc (n=
Jaime Marty   +21 more
wiley   +1 more source

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