Results 41 to 50 of about 505,478 (275)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

A Common Fixed Point Theorem for Two Random Operators using Random Mann Iteration Scheme [PDF]

, 2013
: In this paper, we proved that if a random Mann iteration scheme is defined by two random operators is convergent under some contractive inequality the limit point is a common fixed point of each of two random operators in Banach space.
Dhakde, Alkesh Kumar, Magarde, Devkrishna, Saluja, S.   +2 more
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Several Fixed Point Theorems in Convex b-Metric Spaces and Applications

Mathematics, 2020
Our paper is devoted to indicating a way of generalizing Mann’s iteration algorithm and a series of fixed point results in the framework of b-metric spaces.
Lili Chen, Chaobo Li, Radoslaw Kaczmarek, Yanfeng Zhao   +3 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Mann-Iteration Process for Power Flow Calculation of Large-Scale Ill-Conditioned Systems: Theoretical Analysis and Numerical Results

IEEE Access, 2021
Power Flow solution of realistic ill-conditioned systems has recently attracted huge attention. Nevertheless, there are still some gaps in this field.
Marcos Tostado-Veliz, Hany M. Hasanien, Rania A. Turky, Abdulaziz Alkuhayli, Salah Kamel, Francisco Jurado   +5 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

A remark concerning the paper "An equivalence between the convergence of Ishikawa, Mann and Picard iterations"

Journal of Numerical Analysis and Approximation Theory, 2004
In this note we show that a result previously obtained by us [An equivalence between the convergences of Ishikawa, Mann and Picard iterations, Math. Commun., 8, pp.~15--22, 2003], holds under weaker assumptions.
Ştefan M. Şoltuz
doaj   +2 more sources

On the Mann-type iteration and the convex feasibility problem

, 2008
The weak and strong convergence of a sequence generated by a Mann-type iteration are investigated in the frame of a real Hilbert space.
Popirlan, Cristina, Măruşter, Ştefan
core   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source