Cytosolic Phospholipase A2α and Eicosanoids Regulate Expression of Genes in Macrophages Involved in Host Defense and Inflammation [PDF]
Acknowledgments: We thank Dr. Robert Barkley and Charis Uhlson for mass spectrometry analysis. Funding: This work was supported by grants from the National Institutes of Health HL34303 (to C.C.L., R.C.M. and D.L.B), DK54741 (to J.V.B.), GM5322 (to D.L.W.)
Bonventre, Joseph V. +9 more
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Role of Protein Glycosylation in Candida parapsilosis Cell Wall Integrity and Host Interaction
Candida parapsilosis is an important, emerging opportunistic fungal pathogen. Highly mannosylated fungal cell wall proteins are initial contact points with host immune systems.
Luis A. Pérez-García +14 more
doaj +1 more source
Application of novel analytical ultracentrifuge analysis to solutions of fungal mannans [PDF]
Polysaccharides, the most abundant biopolymers, are required for a host of activities in lower organisms, animals, and plants. Their solution characterization is challenging due to their complex shape, heterogeneity, and size.
Adams, Gary G. +7 more
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Serological Specificity of Yeast Mannan [PDF]
SUMMARY: Soluble serologically active preparations extracted by various methods from Saccharomyces spp. showed the group specificity previously detected by agglutination tests with whole cells. The antigenic properties of the four serological groups of the genus Saccharomyces are probably determined by the cell wall mannan.
I, Campbell, R H, Gilmour
openaire +2 more sources
Evolution and functional characterization of CAZymes belonging to subfamily 10 of glycoside hydrolase family 5 (GH5_10) in two species of phytophagous beetles. [PDF]
Hemicelluloses, such as xyloglucan, xylan and mannans, consist of a heterogeneous array of plant-derived polysaccharides that form the plant cell wall.
André Busch +3 more
doaj +1 more source
Phosphomannosyl receptors may participate in the adhesive interaction between lymphocytes and high endothelial venules. [PDF]
Normal and malignant lymphocytes can migrate from the bloodstream into lymph nodes and Peyer's patches. This process helps distribute normal lymphocytes throughout the lymphoid system and may provide a portal of entry for circulating malignant cells.
Rosen, SD, Stoolman, LM, Tenforde, TS
core +1 more source
The fungal cell wall contains glycoproteins that interact with the host immune system. In the prominent pathogenic yeast Candida albicans, Pmr1 acts as a Golgi-resident ion pump that provides cofactors to mannosyltransferases, regulating the synthesis of
María J. Navarro-Arias +19 more
doaj +1 more source
Candida albicans Yeast, Pseudohyphal, and Hyphal Morphogenesis Differentially Affects Immune Recognition [PDF]
The authors thank Amy Whittington for preliminary experiments on in vitro induction of pseudohyphae and Mihai Netea for discussions. The authors also thank Michael Weig for the pga29 strains. Funding NG and AW were supported by the Wellcome Trust (086827,
Bailey +79 more
core +2 more sources
Role of Protein Mannosylation in the Candida tropicalis-Host Interaction
Mannans are components of the fungal wall attached to proteins via N- or O-linkages. In Candida albicans, Och1 is an α1,6-mannosyltransferase that adds the first mannose unit to the N-linked mannan outer chain; whereas Pmr1 is an ion pump that imports ...
Marco J. Hernández-Chávez +10 more
doaj +1 more source
Mannans are polysaccharide antigens expressed on the cell wall of different fungal species including Saccharomyces cerevisiae and Candida spp. These fungi are components of the normal intestinal microflora, and the presence of antibodies to fungal ...
Vadim B. Krylov +8 more
doaj +1 more source

