Results 51 to 60 of about 1,232 (199)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
David Hume on custom and habit and living with skepticism
Daimon, 2011 This article is an exploration of David Hume's philosophy of custom and habit as a way of living with skepticism. For Hume, man is a habit-forming animal, and all politics and history take place within a history of custom and habit.
John Christian Laursen
doaj
Mapping Arabs and Their Culture in Gertrude Bell’s Syria: The Desert and the Sown
Ilha do DesterroThis article fleshes out the representation of Arabs and their culture in Gertrude Bell’s Syria: The Desert and the Sown (1907). Even though this travel book has already been examined, the nuanced ways in which Bell employs the narrative space to ...
Farah Ghaderi, Mohaimin Ahmed Salman
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
AKULTURASI BUDAYA ACEH DAN ARAB DALAM KEUNDURI MULOD
Forum Ilmu Sosial, 2012 Maulid (the celebration of the birth of the Prophet Muhammad) has been form of acculturation of tradition (custom) in Aceh. At the level of culture and structure, it is called a complex trait. Traditions applied follow the tradition set in Arab countries.
Fakhrurrazi Fakhrurrazi
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
VeredasEste artigo realiza uma leitura da sociedade de consumo, à luz da crítica corsária de Pier Paolo Pasolini, tal como ela é retratada no romance A caverna (2000), de José Saramago.
Letícia Costa Feiteira
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