Results 201 to 210 of about 173,926 (294)

Transglutaminase‐mediated cytokeratin modifications implicated in bile‐acid‐induced hepatocyte death

open access: yesThe FEBS Journal, EarlyView.
Cholestasis and bile‐acid exposure enhance expression and activity of protein crosslinking enzymes TG1 and TG2 in hepatocytes. Substrate proteins were identified by mass spectrometry using biotin‐labeled peptides (pepK5/pepT26) or amine donor (biotinylated pentylamine; BPA). Crosslinking‐induced aggregation and fragmentation of keratin 18 and 8 (K18/K8)
Hideki Tatsukawa   +4 more
wiley   +1 more source

Crystal structure of plant γ‐glutamyl peptidase 1: implications for sulfur metabolism and secondary metabolite biosynthesis

open access: yesThe FEBS Journal, EarlyView.
The crystal structures of Arabidopsis thaliana γ‐glutamyl peptidase 1 (GGP1), including the covalent intermediate state, were determined. GGP1 is involved in both glutathione degradation in the primary metabolism and glutathione conjugate processing in the secondary metabolism of glucosinolate and camalexin biosynthesis.
Kosei Sone   +7 more
wiley   +1 more source

A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer

open access: yesThe FEBS Journal, EarlyView.
Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge   +3 more
wiley   +1 more source

Deep clinical, genetic, and serum biomarker profiling indicates glial and neuronal pathology in primary brain calcification. [PDF]

open access: yesBrain Commun
Schwahn J   +32 more
europepmc   +1 more source

PROVINCIALISING BERLIN IN MENSCHEN IM HOTEL

open access: yesGerman Life and Letters, EarlyView.
ABSTRACT In this article, I take the peculiar source of Vicki Baum's Menschen im Hotel (1929) in a Southern Moravian town as a starting point to reveal the ways in which the hierarchies between metropolis and province are negotiated and complicated by the novel.
Meindert Peters
wiley   +1 more source

Abdominal pressure pain thresholds correlate with postoperative pain intensity. [PDF]

open access: yesSci Prog
Ghanad E   +9 more
europepmc   +1 more source

Carotid Intima‐Media Thickness as a Marker of Subclinical Atherosclerosis in Adolescents With Severe Haemophilia

open access: yesHaemophilia, EarlyView.
ABSTRACT Background The clinical focus of haemophilia has expanded beyond bleeding outcomes to encompass long‐term comorbidities such as cardiovascular disease (CVD). However, it remains unclear when vascular changes begin in this population. Carotid intima‐media thickness (cIMT), a validated, non‐invasive marker of subclinical atherosclerosis, may ...
Alyson Trillo   +5 more
wiley   +1 more source

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