Results 171 to 180 of about 39,781 (235)

Investigating Factors Associated With Spontaneous Remission in Individuals With Alcohol Use Disorder-Results From a Multi-Site Longitudinal Cohort Study. [PDF]

open access: yesAddict Biol
Zaiser J   +18 more
europepmc   +1 more source

Plasma PlGF as a Potential Biomarker in Ramucirumab‐Based Second‐Line Therapy for Advanced Gastroesophageal Adenocarcinoma: Exploratory Biomarker Analysis from the Phase II Part of the RAMIRIS Trial

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1817-1828, 1 October 2026.
Antiangiogenic treatment with ramucirumab is a standard second‐line option in advanced gastric and gastroesophageal junction adenocarcinoma. However, reliable biomarkers are currently lacking. This exploratory biomarker analysis of the RAMIRIS trial suggests that elevated baseline and early on‐treatment levels of the pro‐angiogenic placental growth ...
Jurek Hille   +17 more
wiley   +1 more source

Elevated leucine-rich alpha-2 glycoprotein levels and mortality risk in end-stage renal disease: evidence for gender differences. [PDF]

open access: yesClin Kidney J
Xiong J   +9 more
europepmc   +1 more source

A Serum lncRNA Signature Determines Oncogenic YAP Activity in Cancer Patients

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1829-1843, 1 October 2026.
Long non‐coding RNAs (lncRNAs) signatures are promising cancer biomarkers, since their dysregulation in tumors is reflected in body fluids. In this study, next‐generation sequencing, bioinformatics, and gene expression data were combined to investigate an lncRNA signature linked specifically to the cancer‐promoting YAP in several cancer types ...
Fabian Rose   +24 more
wiley   +1 more source

Microscale FFT‐based modeling of artificial porous microstructures and analysis of macroscopic models under varying loading scenarios

open access: yesGAMM-Mitteilungen, Volume 49, Issue 3, September 2026.
Abstract This article investigates the modeling of metallic isotropic porous materials by evaluating and comparing macroscopic and microstructure‐resolved simulation approaches. At the macroscopic level, different variants of the Deshpande‐Fleck (DF) model are implemented to describe the elastoplastic behavior of metallic porous materials.
Julian Dahler   +2 more
wiley   +1 more source

Hemodynamic effects of red blood cell transfusion in patients with hemato-oncologic diseases. [PDF]

open access: yesFront Med (Lausanne)
Yazdani B   +9 more
europepmc   +1 more source

The Cancer Immunotherapy Thromboembolism Assessment: A Novel Score for Predicting Thromboembolic Events in Melanoma Patients Treated With Immune Checkpoint Inhibition

open access: yesInternational Journal of Cancer, Volume 159, Issue 5, Page 1337-1344, 1 September 2026.
Although immune checkpoint inhibitors (ICI) have transformed metastatic melanoma treatment, thromboembolic events (TEEs) remain a serious complication. Moreover, existing risk assessment models were developed prior to ICI use and lack clinical validation.
Tim Zell   +12 more
wiley   +1 more source

Flow-cytometric profiling of large extracellular vesicles as immunophenotypic biomarkers in head and neck squamous cell carcinoma. [PDF]

open access: yesCancer Immunol Immunother
Büntzel J   +10 more
europepmc   +1 more source

Aberrant alternative splicing of purinergic receptor P2RX4 prevents sensitivity towards combinatorial treatment in colorectal and pancreatic cancer

open access: yesThe Journal of Pathology, Volume 270, Issue 1, Page 55-68, September 2026.
Abstract Recently, we suggested the combination of chemotherapy and P2RX4 inhibition as a promising novel therapeutic approach for P2RX4‐expressing epithelial tumors to prevent paracrine resistance. Here, we aimed to assess whether determining P2RX4 expression status in colorectal and pancreatic cancer patients would allow stratification of potentially
Christoph Steup   +12 more
wiley   +1 more source

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