MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou +9 more
wiley +1 more source
Novel, non-invasive technique for fracture reduction in rare pertrochanteric femur fractures in patients with ipsilateral above-knee amputation: a technical report. [PDF]
Vadgaonkar A +6 more
europepmc +1 more source
ABSTRACT Apolipoprotein B (ApoB) is a key marker of atherogenic lipoprotein burden, but conventional plasma‐based testing requires venous sampling and centralized laboratory infrastructure. Dried blood spot (DBS) sampling offers a minimally invasive alternative suitable for decentralized settings.
Bronwyn Pitampersad +4 more
wiley +1 more source
QuAPPro: an R shiny app for quantification and alignment of polysome profiles. [PDF]
Schiller C +5 more
europepmc +1 more source
What's new? Pancreatic ductal adenocarcinoma is characterized by a dense extracellular matrix, and how invasive tumor cells overcome such biomechanical constraints remains unclear. This study identifies the actin‐related protein 2/3 complex as a key regulator of pancreatic ductal adenocarcinoma invasiveness, driving fibroblast migration through β1 ...
Xiufen Yang +15 more
wiley +1 more source
Retrospective study of mechanical complications after cephalomedullary nail implantation from 2019 to 2024 following per-, sub- or intertrochanteric femur fractures. [PDF]
Blümke A +11 more
europepmc +1 more source
Exercise Modalities to Preserve Muscle Mass and Bone Health After Metabolic Bariatric Surgery
ABSTRACT Background Metabolic bariatric surgery (MBS) effectively reduces fat mass (FM), but how to best preserve muscle and bone mass after MBS is unknown. Objective This study aimed to evaluate the effect of aerobic, resistance and combined exercise regimens on body composition, bone mineral density (BMD) and physical function in adults following MBS.
Ariela Goldenshluger +19 more
wiley +1 more source
A decade of triage with the Manchester Triage System-The MTS big data study. [PDF]
Gräff I, Berger M, Schmid M, Kogej M.
europepmc +1 more source
ABSTRACT Context Screening morning serum cortisol is used to select patients for ACTH stimulation testing to diagnose adrenal insufficiency (AI) but may be affected by pre‐analytical factors. Careful consideration to discontinue confounding medications beforehand may preclude the need for subsequent stimulation testing.
Christopher J. Symonds +2 more
wiley +1 more source
Bioequivalence of netupitant and palonosetron (NEPA) oral suspension and hard capsules in healthy individuals: results from an open-label, randomized, two-treatment, four-period, two-sequence replicative design trial. [PDF]
Gasanin E, Bezzo R, Spinelli T, Seitz F.
europepmc +1 more source

