Results 131 to 140 of about 152,345 (256)

Impact of the GouM transporter on secondary metabolism activation and production yield in Streptomyces noursei strain CK‐15

New Plant Protection, EarlyView.
Overexpression of the gouM transporter gene in Streptomyces noursei CK‐15 enhances gougerotin production by 114% and activates silent biosynthetic gene clusters. This finding links transporter activity to metabolite efflux and secondary metabolism, offering a strategy for natural product discovery and strain optimization.
Qianying Zhou, Hua Yu, Rouhallah Sharifi, Muhammad Usman, Shun Lai Ei, Abdel‐Hamied M. Rasmey, Beibei Ge   +6 more
wiley   +1 more source

Discovery of edodine, a natural compound from Lentinula edodes with antibacterial activity for the biological control of fire blight pathogen Erwinia amylovora

Pest Management Science, EarlyView.
Novel edodine was identified from Lentinula edodes HK761, exhibiting biocontrol potential against fire blight by affecting motility, intracellular ATP level, and cell division of Erwinia amylovora. Abstract BACKGROUND In the search for biological resources with antibacterial activity against Erwinia amylovora, the culture filtrate of Lentinula edodes ...
Yeong Seok Kim, Jae Woo Han, Bomin Kim, Chunggeon Lee, Daeui Park, Jaehyuk Choi, Gyung Ja Choi, Hun Kim   +7 more
wiley   +1 more source

Programmable 3D Microfluidics Reveals Motility‐Driven Antibiotic Resistance Evolution in Gradients

Small, EarlyView.
Using a programmable microfluidic platform, this study shows that bacterial motility is crucial for resistance development in heterogeneous antibiotic landscapes. Motile Escherichia coli randomly migrates along antibiotic gradients, and sufficient movement is required for resistance to emerge.
Xiaobo Li, Jianan Yin, Yanqing Song, Andrew Glidle, William Sloan, He Huang, Maggie Cusack, Cindy J. Smith, Huabing Yin   +8 more
wiley   +1 more source

Unveiling the interplay between methylglyoxal and plant growth under abiotic adversity via a red‐emissive probe operated by a ring‐closure mechanism

Smart Molecules, EarlyView.
BH‐PDN is a red‐emissive fluorescent probe that enables methylglyoxal (MGO) detection via a ring‐closure‐triggered turn‐on response. Probe‐based imaging uncovered prominent MGO buildup in Arabidopsis thaliana roots exposed to salinity, extreme temperatures and drought.
Yu‐Long Li, Xin‐Hui‐Zi Li, Ting‐Ting Liu, Yuan Qiu, Xiao‐Gang Luo, Qi Sun, Shu‐Jing Yu   +6 more
wiley   +1 more source

Overexpression of mannitol-1-phosphate dehydrogenase increases mannitol production and confers salt and chilling tolerance in transgenic petunia cv. Mitchell [PDF]

, 2000
2000 Spring.Covers not scanned.Includes bibliographical references.Diploid petunia plants (Petunia hybrid, cv. Mitchell) transformed with a bacterial gene (mt/ D) encoding mannitol-1-phosphate dehydrogenase enzyme (MTL D), resulting in high mannitol ...
Hughes, Harrison G., committee member, Jiang, Yu-Jen, author, Stushnoff, Cecil, advisor, Ishimaru, Carol, committee member, Wallner, Stephen J., committee member   +4 more
core  

Benzimidazole Anthelmintic Compounds Albendazole and Fenbendazole Show Distinct Toxicity on the Nitrogen Fixing Bacterium Mesorhizobium loti and Its Symbiosis With Lotus japonicus

Environmental Toxicology, EarlyView.
ABSTRACT Veterinary medicines, which reach the soil mostly through the application of contaminated manures, can affect beneficial soil microorganisms, such as nitrogen‐fixing rhizobia bacteria, which engage in important symbiotic associations with plants.
Polyxeni Gorgia, Stathis Lagos, Christina N. Nikolaou, Nikoleta Basdeki, Christos Papadopoulos, Dimitrios G. Karpouzas, Daniela Tsikou   +6 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Perilymph Gusher in Cochlear Implantation Surgery: An Algorithm for Management

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Perilymph leak is considered a major complication of cochlear implantation (CI) surgery and can lead to surgical difficulties and postoperative morbidities. This study is aimed to formulate an algorithm for better management of perilymph leak in cases of CI. Methods This is a retrospective study conducted in our tertiary institute on
Ahmed Abdelmoneim Teaima, Lobna El Fiky, Badr Eldin Mostafa, Mina Fayez Saleeb, Ossama Mustafa Mady   +4 more
wiley   +1 more source

Comparative Analysis of Stress Adaptation in the Yeast Microbiome of Cactus

Yeast, EarlyView.
Yeasts and related fungi isolated from cacti or nearby non‐cactus plants were characterized phenotypically and genomically, revealing differences that hint at modes of adaptation to the cactus host. ABSTRACT Together with other fungi, yeasts make up a significant component of the plant microbiome. As the planet warms, cacti expand their range.
Alya N. Hussain, Kevin T. Fotso, Michael A. McMurray   +2 more
wiley   +1 more source

Metabolomic Mapping of Greek Olive Leaves by Untargeted NMR-Based Profiling and LC-HRMS Dereplication. [PDF]

Anal Sci Adv
ABSTRACT Olive tree leaves are phytochemically rich yet insufficiently valorised in terms of systematic cultivar‐based characterisation and exploitation, and are an abundant olive industry side‐product. This study represents the first large‐scale metabolome mapping based on 340 leaf extracts from five major Greek cultivars (Amfissis, Koroneiki, Manaki,
Lianza M, Beteinakis S, Siderakis V, Stathopoulos P, Hatzakis E, Halabalaki M.   +5 more
europepmc   +2 more sources