Results 171 to 180 of about 127,314 (247)

Central Diabetes Insipidus and Brain Herniation Secondary to Cryptococcal Meningitis in a Dog

Clinical Case Reports, Volume 14, Issue 7, July 2026.
Patient CSF cytology consistent with Cryptococcus fungal infection with eosinophilic inflammation. ABSTRACT Central diabetes insipidus (CDI) should be considered in neurologic patients with persistent polyuria and rising sodium concentrations despite appropriate fluid therapy. Earlier recognition, serial urine concentration monitoring, and desmopressin
Owen Hurst, Alicia Mastrocco, Jennifer Prittie   +2 more
wiley   +1 more source

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

Chirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu   +1 more
wiley   +1 more source

The effect of preemptive intravenous paracetamol-mannitol on postoperative analgesia and quality of recovery in elderly patients undergoing total hip arthroplasty. [PDF]

BMC Anesthesiol
Zhou X, Jing J, Xu P, Wu Q, Chen M.
europepmc   +1 more source

Optimization of Cultivation Parameters for Scale-Up Production of <i>Streptomyces recifensis</i> SN1E1. [PDF]

J Microbiol Biotechnol
Lee SI, Kwak YS.
europepmc   +1 more source

Icariin Alleviates Diabetes‐Associated Cognitive Dysfunction Through Modulation of LCN2–MEK/ERK Signaling‐Associated Neuroinflammation

CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
Icariin protects against diabetes‐associated cognitive dysfunction by effectively inhibiting the LCN2–MEK/ERK axis and alleviating neuroinflammation. These findings demonstrate that targeting this signaling pathway with icariin may offer a promising strategy for treating cognitive impairment in diabetes. ABSTRACT Objective Diabetes‐associated cognitive
Xinyi Jiao, Yutong Ren, Ziman Yu, Junxiong Zhou, Danyang Wang, Bin Yan, Guoqing Tian   +6 more
wiley   +1 more source

Mex‐3 RNA‐binding family member A limits macrophage ferroptosis‐associated injury linked to the SLC7A11/GPX4 pathway in diabetic atherosclerosis

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Diabetes reduces macrophage MEX3A and aggravates atherosclerotic plaque instability. MEX3A stabilises Slc7a11 and Gpx4 mRNAs to sustain SLC7A11/GPX4 antioxidant defence. MEX3A deficiency promotes macrophage ferroptosis, lipid peroxidation and mitochondrial injury. Ferrostatin‐1 partially attenuates ferroptotic injury and diabetic plaque destabilisation.
Yanpeng Ma, Jing Liu, Yujie Xing, Shuo Pan, Begench H. Annayev, We Wu, Xiqiang Wang, Zhongwei Liu   +7 more
wiley   +1 more source

Microwave-Assisted Wet Granulation for Engineering Rice Starch-Mannitol Co-Processed Excipients for Direct Compression of Orally Disintegrating Tablets. [PDF]

Pharmaceutics
Trisopon K, Saokham P.
europepmc   +1 more source

Phytochemical Composition and Potential Bioactivity With ADMET Analysis of Selected Species From Myrtaceae Family

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 1002-1029, July 2026.
Investigation of four medicinal plants of the family Myrtaceae. ABSTRACT Compounds derived from natural sources continue to serve as chemical scaffolds for designing prophylactic/therapeutic options for human healthcare. This study aimed to evaluate the phytochemical composition, antioxidant potential, in vitro anti‐inflammatory, antibacterial and ...
Archana Joshi, Vaishnavi Rawat, Ravendra Kumar, Stefania Garzoli, Anil Kumar Pant, Marcin Stocki, Valery A. Isidorov, Om Prakash, Dharmendra Singh Rawat   +8 more
wiley   +1 more source

Choice of cardioplegia influences metabolomics of human cardiac tissue. [PDF]

Proc Natl Acad Sci U S A
Tanosaki S, Zhang Y, Bedi K, Margulies K, Cox JE, Arany Z, Abel ED.   +6 more
europepmc   +1 more source

Bovine Milk–Derived Extracellular Vesicles as Emerging Drug Delivery Platforms: Current Advances, Applications and Challenges

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs) are nanosized lipid bilayer particles naturally secreted by cells, mediating intercellular communication and transporting diverse bioactive molecules. Among alternative EV sources, bovine milk‐derived EVs (BMEVs) have emerged as promising platforms for drug delivery due to their accessibility, scalability ...
Martina Brattini, Michelle D'Urso, Sofia Mariotto, Elena Butturini   +3 more
wiley   +1 more source