Results 251 to 260 of about 175,359 (294)

NMR based clinical metabolomics revealed altered lipid and sugar metabolism in systemic sclerosis with implications for diagnosis and therapeutic strategies. [PDF]

Sci Rep
Singh G, Ahmed S, Dubey D, Rai MK, Rawat A, Agarwal V, Kumar D.   +6 more
europepmc   +1 more source

Immunomodulatory Biomaterials for Bone and Soft Tissue Chronic Inflammation Diseases

Small Science, EarlyView.
This review analyzes immunomodulatory biomaterial strategies for treating chronic inflammatory disorders in bone and soft tissues. It explores emerging mechanisms for resolving inflammation while promoting tissue regeneration, offering insights for developing targeted immunotherapeutic approaches that bridge material science with immunology for ...
Yiming Li, Xudong Xie, Chong Ding, Shengming Zhang, Liangcong Hu, Bobin Mi, Mengfei Liu, Guohui Liu   +7 more
wiley   +1 more source

Zebrafish models for congenital disorders of glycosylation (CDG): a systematic review. [PDF]

Orphanet J Rare Dis
Gandoy-Fieiras N, Quiroga MI, Sánchez L.   +2 more
europepmc   +1 more source

Mannose Oligosaccharide‐Conjugated In Situ Pore‐Forming Injectable Hydrogels for Rheumatoid Arthritis Treatment by Reprogramming Macrophage Extracellular Vesicles

Small Methods, EarlyView.
Design of an injectable porous hydrogel modulating macrophages and their secreted EVs for joint defect repair in the pathology of rheumatoid arthritis. a) The solution containing HA and CS‐MOS, upon mixing with a crosslinker solution, undergoes porous hydrogel formation with the escape of generated CO₂ gas.
Anan Zhang, Yifan Ma, Yutong Liu, Shiyan Dong, Michelle Najarro Torres, Betty Y.S. Kim, Changsheng Liu, Lili Sun, Yuan Yuan, Wen Jiang   +9 more
wiley   +1 more source

Optimizing the treatment and valorization of spent coffee grounds (SCGs) through the integration of sequential pretreatment steps, enzymatic hydrolysis, and selective fermentation. [PDF]

Food Chem X
Cho EJ, Lee WH, Lee YG, Van Ta Q, Kim HY, Bae HJ.   +5 more
europepmc   +1 more source

Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers

Small Methods, EarlyView.
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz, Nima Pourafzal, Audrey T. Zhu, Zhongyuan Guo, Ronnie H. Fang, Liangfang Zhang   +5 more
wiley   +1 more source

Immunopathology in PMM2-CDG: Defective glycosylation impact in the TNFα -TNFR1 signalling pathway. [PDF]

Front Immunol
Pascoal C, Granjo P, Kodríková R, Falcão M, Santos AC, Teodoro I, Pakanová Z, Nemčovič M, Mucha J, Castro-Caldas M, Grosso AR, Dos Reis Ferreira V, Videira PA.   +12 more
europepmc   +1 more source

Cell‐Free Protein Crystallization Enables Rapid Structure Determination of Disaccharides and Trisaccharides Using Galectin‐10 Crystals

Small Structures, EarlyView.
Galectin‐10 crystals prepared by cell‐free protein crystallization serve as the scaffold to capture the saccharides to determine the atomic‐resolution structure of a trisaccharide bound to protein. Molecular dynamics simulation combined with the mutation of scaffold crystals offers insights into how the binding site architecture modulates saccharide ...
Mariko Kojima, Xinchen Yao, Satoshi Abe, Tadaomi Furuta, Kunio Hirata, Ririko Kobayashi, Taiga Suzuki, Takafumi Ueno   +7 more
wiley   +1 more source

Construction of Yeast One-Hybrid Library of <i>Dendrobium huoshanense</i> and Screening of Potential Transcription Factors Regulating <i>DhPMM</i> Gene Expression. [PDF]

Biomolecules
Wu J, Wang S, Xing S, Peng D.
europepmc   +1 more source