Results 131 to 140 of about 30,203 (240)

Bowel Urgency Improvement Correlates With Clinical, Biochemical, and Intestinal Ultrasound Improvements in Inflammatory Bowel Disease: A Cross Sectional Multicenter Study

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Bowel urgency (BU) is reported by over 80% of patients with ulcerative colitis (UC) and 60% of those with Crohn's disease (CD). However, the impact of advanced therapies on BU has not been consistently evaluated. Objectives To assess the effect of advanced therapies on BU improvement in patients with UC and CD.
Ferdinando D'Amico   +17 more
wiley   +1 more source

174 - The Predictive Value of Digital Rectal Examination (DRE) and Balloon Expulsion Test (BET) in Diagnosing Dyssynergia Defecation

open access: yesContinence
Hypothesis / aims of study: This study investigates dyssynergia defecation (DD), a significant contributor to persistent constipation caused by impaired pelvic floor relaxation, particularly in patients requiring pelvic floor surgery.
d maryam   +4 more
doaj   +1 more source

Persistence of abnormal gastrointestinal motility after operation for Hirschsprung's disease [PDF]

open access: yes, 2000
CLOUSE RE   +5 more
core   +1 more source

Naldemedine for the Prevention of Recurrent Acute Pancreatitis: A Randomised, Double‐Blind, Placebo‐Controlled Trial

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background and aims No medications are currently approved for the prevention of recurrent acute pancreatitis. This trial evaluated whether naldemedine, a peripherally acting μ‐opioid receptor antagonist, reduces the risk of acute pancreatitis in patients with recurrent acute pancreatitis. Methods This was a multicentre, double‐blinded, placebo‐
Mathias E. Cook   +13 more
wiley   +1 more source

Anorectal manometry — How to perform and interpret manometry

open access: yesContinence
Anorectal manometry is the most widely used technique for detecting abnormalities of sphincter function and recto-anal coordination. It enables the investigation of defaecatory difficulties, including anal incontinence and evacuatory difficulties, the ...
Tanzeela Gala   +6 more
doaj   +1 more source

Prevalence and Clinical Characteristics of Systemic Sclerosis in Alaska Native and American Indian Peoples in Alaska

open access: yesACR Open Rheumatology, Volume 8, Issue 1, January 2026.
Objective Systemic sclerosis (SSc) is known to exhibit significant epidemiologic and clinical variation. This study aimed to describe the clinical and epidemiologic characteristics of SSc in Alaska Native and American Indian (AN/AI) individuals in Alaska.
Vivek R. Mehta   +5 more
wiley   +1 more source

Mechanoluminescent Aluminum Nitride Crystal for Super‐Sensitive Optical Manometry, Thermometry and Force Sensing

open access: yesAdvanced Materials, Volume 38, Issue 1, 2 January 2026.
This study reports the first discovery of intrinsic mechanoluminescence in undoped AlN crystals, accompanied by pronounced photoluminescence and persistent luminescence. It further demonstrates a defect‐emission–driven multifunctional optical sensing platform for force, pressure, and temperature detection, achieving exceptional sensitivities.
Teng Zheng   +11 more
wiley   +1 more source

Nationwide Survey of the Surgical Treatment for Hiatal Hernia in Japan

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 1, Page 113-127, January 2026.
This nationwide study of 960 hiatal hernia surgeries in Japan found that patients with Type I hernia had distinct characteristics and more favorable surgical outcomes compared to Types II–IV. Postoperative dysphagia was significantly associated with Types II–IV, preoperative dysphagia, and esophageal strictures, highlighting the need for careful ...
Soji Ozawa   +8 more
wiley   +1 more source

A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa   +7 more
wiley   +1 more source

A Review of the Mechanisms of Action of the Herbal Medicine, STW 5‐II, Underlying Its Efficacy in Disorders of Gut–Brain Interaction

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 1, January 2026.
The pathophysiology of functional dyspepsia and irritable bowel syndrome includes altered motility, secretion, sensitivity to sensory signals, impaired epithelial barrier function, inflammation, and gut dysbiosis. The phytomedicine, STW 5‐II, represents a multi‐targeted approach, addressing these pathophysiologies.
Anita Annaházi   +6 more
wiley   +1 more source

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