Results 131 to 140 of about 30,203 (240)
ABSTRACT Background Bowel urgency (BU) is reported by over 80% of patients with ulcerative colitis (UC) and 60% of those with Crohn's disease (CD). However, the impact of advanced therapies on BU has not been consistently evaluated. Objectives To assess the effect of advanced therapies on BU improvement in patients with UC and CD.
Ferdinando D'Amico +17 more
wiley +1 more source
Hypothesis / aims of study: This study investigates dyssynergia defecation (DD), a significant contributor to persistent constipation caused by impaired pelvic floor relaxation, particularly in patients requiring pelvic floor surgery.
d maryam +4 more
doaj +1 more source
Persistence of abnormal gastrointestinal motility after operation for Hirschsprung's disease [PDF]
CLOUSE RE +5 more
core +1 more source
ABSTRACT Background and aims No medications are currently approved for the prevention of recurrent acute pancreatitis. This trial evaluated whether naldemedine, a peripherally acting μ‐opioid receptor antagonist, reduces the risk of acute pancreatitis in patients with recurrent acute pancreatitis. Methods This was a multicentre, double‐blinded, placebo‐
Mathias E. Cook +13 more
wiley +1 more source
Anorectal manometry — How to perform and interpret manometry
Anorectal manometry is the most widely used technique for detecting abnormalities of sphincter function and recto-anal coordination. It enables the investigation of defaecatory difficulties, including anal incontinence and evacuatory difficulties, the ...
Tanzeela Gala +6 more
doaj +1 more source
Objective Systemic sclerosis (SSc) is known to exhibit significant epidemiologic and clinical variation. This study aimed to describe the clinical and epidemiologic characteristics of SSc in Alaska Native and American Indian (AN/AI) individuals in Alaska.
Vivek R. Mehta +5 more
wiley +1 more source
This study reports the first discovery of intrinsic mechanoluminescence in undoped AlN crystals, accompanied by pronounced photoluminescence and persistent luminescence. It further demonstrates a defect‐emission–driven multifunctional optical sensing platform for force, pressure, and temperature detection, achieving exceptional sensitivities.
Teng Zheng +11 more
wiley +1 more source
Nationwide Survey of the Surgical Treatment for Hiatal Hernia in Japan
This nationwide study of 960 hiatal hernia surgeries in Japan found that patients with Type I hernia had distinct characteristics and more favorable surgical outcomes compared to Types II–IV. Postoperative dysphagia was significantly associated with Types II–IV, preoperative dysphagia, and esophageal strictures, highlighting the need for careful ...
Soji Ozawa +8 more
wiley +1 more source
A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa +7 more
wiley +1 more source
The pathophysiology of functional dyspepsia and irritable bowel syndrome includes altered motility, secretion, sensitivity to sensory signals, impaired epithelial barrier function, inflammation, and gut dysbiosis. The phytomedicine, STW 5‐II, represents a multi‐targeted approach, addressing these pathophysiologies.
Anita Annaházi +6 more
wiley +1 more source

