Results 161 to 170 of about 84,950 (309)

Administration of nivolumab plus ipilimumab: Infusion of the fixed‐ratio combination versus sequential infusions in two randomized controlled trials of metastatic melanoma (CheckMate 742) and renal cell carcinoma (CheckMate 800)

open access: yesCancer, Volume 131, Issue 14, 15 July 2025.
Abstract Background Immune checkpoint inhibitors can be coadministered as a fixed‐ratio combination (FRC) or administered as sequential infusions (ASI). Two randomized, open‐label trials compared nivolumab + ipilimumab as a FRC versus ASI in patients with melanoma or renal cell carcinoma.
Alexander M. Menzies   +19 more
wiley   +1 more source

Drug‐Coated Balloons Versus Non‐Coated Balloons for Side Branch Treatment in Bifurcation Lesions: A Systematic Review and Meta‐Analysis

open access: yesCatheterization and Cardiovascular Interventions, Volume 106, Issue 1, Page 530-539, July 1, 2025.
ABSTRACT Background Coronary bifurcation lesions (CBL) account for ~20% of percutaneous coronary interventions (PCI). When using provisional stenting, optimal management of a diseased side branch (SB) remains debated. Drug‐coated balloons (DCBs) are an emerging option, but data on their role in CBL PCI are limited.
Matteo Rocchetti   +7 more
wiley   +1 more source

A Randomized Phase 1 Study Evaluating Pharmacokinetics, Safety, and Tolerability of a High‐Concentration, Long‐Acting Cabotegravir Formulation in Adults Without HIV

open access: yesClinical Pharmacology in Drug Development, Volume 14, Issue 7, Page 528-541, July 2025.
Abstract Long‐acting (LA) cabotegravir 200‐mg/mL (CAB200) injections are approved for HIV‐1 prevention and as a complete LA HIV‐1 treatment regimen with rilpivirine. A high‐concentration suspension formulation, cabotegravir 400 mg/mL (CAB400‐D), was developed to enable less frequent dosing and self‐administration. This phase 1, double‐blind, randomized
Kelong Han   +16 more
wiley   +1 more source

Implementing a Class of Permutation Tests: The coin Package [PDF]

open access: yes
The R package coin implements a unified approach to permutation tests providing a huge class of independence tests for nominal, ordered, numeric, and censored data as well as multivariate data at mixed scales.
Achim Zeileis   +3 more
core   +1 more source

Adaptive Emergence Patterns of Spot‐Tailed Earless Lizards: Influence of UV Light and Temperature on Diel Activity

open access: yesEcology and Evolution, Volume 15, Issue 7, July 2025.
Our results of spot‐tailed earless lizards (STEL) light‐dependent emergence behavior not only illustrate adaptation to specific environmental cues, but also offer insights into the resilience and adaptability of reptiles inhabiting arid and semiarid ecosystems.
E. Drake Rangel   +5 more
wiley   +1 more source

EAES Rapid Recommendation Update Protocol: TaTME for Rectal Cancer – With ESCP and ESGAR Participation

open access: yesClinical and Public Health Guidelines, Volume 2, Issue 3, July 2025.
ABSTRACT Introduction Transanal total mesorectal excision (TaTME) was developed to overcome anatomical constraints related to TME. The European Association of Endoscopic Surgery (EAES) released clinical recommendations to support gastrointestinal surgeons in the treatment of rectal cancer, but contemporary evidence is available. Questions 1.
Bright Huo   +3 more
wiley   +1 more source

Computing single-, two-stage, and iterative Mantel-Haenszel statistics. [PDF]

open access: yesPsicológica, 1999
Fidalgo A. M.   +2 more
doaj  

Relationship Between Fear of Coronavirus Disease 2019 and Patient Preferences for Medical Services in Ghana: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background The COVID‐19 pandemic has significantly impacted public health, causing fear and influencing individuals' behaviours and attitudes towards healthcare services. This study explores the relationship between fear of COVID‐19 and patient preferences for medical services in Ghana. Design and Methods A cross‐sectional study was undertaken
Nathan Kumasenu Mensah   +9 more
wiley   +1 more source

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