Results 181 to 190 of about 53,615 (314)

Assessment and Benchmarking of Model Informed Approaches in Drug Development for Hemoglobinopathies: A Review of Scientific Advices From January 2000 to December 2024

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.
ABSTRACT Despite the fact that modeling and simulation are now recognized as promising innovative methodologies, their use in the context of development of drugs for sickle cell disease and Thalassemia has not yet been reviewed. Considering the challenges of conducting clinical trials for hemoglobinopathies, our work aims at exploring the current ...
Grace Shalom Govere   +2 more
wiley   +1 more source

An Association Test for Ordinal Outcomes in Clustered Data With Informative Cluster Size

open access: yesPharmaceutical Statistics, Volume 25, Issue 2, March/April 2026.
ABSTRACT In cluster‐correlated data, the number of observations in a cluster can be associated with the outcome from that cluster. This phenomenon is known as informative cluster size which can occur in cluster‐randomized clinical trial data. Several studies have found that ignoring the issue of informative cluster size can produce biased results in ...
Hasika K. Wickrama Senevirathne   +1 more
wiley   +1 more source

Local Versus Systemic Antibiotics for Diabetic Foot Infection—A Systematic Review and Meta‐Analysis

open access: yesJournal of Diabetes, Volume 18, Issue 3, March 2026.
Combined local and systemic antibiotic therapy improved clinical cure rates and shortened healing time in diabetic foot infections compared with systemic therapy alone. However, due to the low quality of existing studies, high‐quality randomized controlled trials are needed to confirm these findings. ABSTRACT Diabetic foot infection (DFI) includes soft
Anas Khan   +4 more
wiley   +1 more source

ANALYSIS OF THE STRUCTURE AND DYNAMICS OF POSTPARTUM DISEASES IN NOVOKUZNETSK (2020-2022)

open access: yesМать и дитя в Кузбассе
Among the causes of maternal mortality in the Russian Federation, infectious and inflammatory diseases after childbirth and abortion occupy fourth position.
Светлана Владимировна Шрамко   +4 more
doaj  

Estimated Impact of Pressure to Conceive on Maternal Depression in Lesotho: A Quasi-experimental Propensity Score Matching using DHS Data. [PDF]

open access: yesArch Womens Ment Health
Jejaw M   +9 more
europepmc   +1 more source

Diagnostic and Therapeutic Impact of FDG‐PET/CT Following MRI Staging in Anal Cancer: A Systematic Review and Meta‐Analysis

open access: yesJournal of Medical Imaging and Radiation Oncology, Volume 70, Issue 2, Page 188-197, March 2026.
ABSTRACT Introduction Accurate staging is essential in anal cancer to guide therapy and prognostication. While MRI remains the modality of choice for local staging, its limitations in assessing nodal and distant metastases have prompted evaluation of FDG PET/CT as an adjunct.
Hugo C. Temperley   +12 more
wiley   +1 more source

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