Results 51 to 60 of about 53,615 (314)
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's phenomenon (RP) and to explore their potential pathophysiologic mechanisms through a mixed disproportionality/clustering analysis from the World Health Organization (WHO) pharmacovigilance database.
Alex Hlavaty +4 more
wiley +1 more source
Sensitivity of Differential Item Functioning (Dif) Detection Method [PDF]
The prime objective of this study is to find out the empirical data about a comparison sensitivity as Scheuneman's Chi-square, Mantel-Haenszel methods and Item Response Theory (IRT) Rasch model in ...
SUDARYONO, S. (SUDARYONO)
core
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate to severe systemic lupus erythematosus (SLE) activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly
Susan Manzi +12 more
wiley +1 more source
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer +4 more
wiley +1 more source
JUSTIFICATIVA E OBJETIVOS: Retenção urinária é uma condição frequente na sala de recuperação pós-anestésica (SRPA). Sobredistensão vesical e consequente lesão do detrusor da bexiga são situações passíveis de prevenção.
Adilson José Dal Mago +4 more
doaj +1 more source
The effects of donepezil in Alzheimer's disease - Results from a multinational trial [PDF]
Donepezil has been shown to be well tolerated and to improve cognition and global function in patients with mild to moderately severe Alzheimer's disease (AD).
Burns, A. +7 more
core +1 more source
Abstract Aim Heart failure (HF) is a highly prevalent condition managed in both primary care (PC) and hospital care (HC)‐based settings. HF patients managed in these two settings may differ in their demography, comorbidities and outcomes, so we aimed to compare the patient management in PC and HC in the Västra Götaland Region (VGR) in Sweden.
Xiaojing Chen +4 more
wiley +1 more source
DIF in Spanish and Mathematics from Costa Rica’s national tests in reported students with ADHD
The detection of differential item functioning (DIF) is fundamental to ensure instruments’ invariance, and, therefore, a better estimate of the construct being measured across the different groups of examinees. The purpose of this research was to provide
Eiliana Montero Rojas +1 more
doaj +1 more source
Further Characterization of the Mitigation of Radiation Lethality by Protective Wounding [PDF]
There continues to be a major effort in the United States to develop mitigators for the treatment of mass casualties that received high-intensity acute ionizing radiation exposures from the detonation of an improvised nuclear device during a radiological
Dynlacht, Joseph R. +5 more
core +1 more source
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou +7 more
wiley +1 more source

