British Journal of Haematology, EarlyView.Bone marrow (BM) involvement in B‐cell non‐Hodgkin lymphoma (B‐NHL) is associated with poor prognosis, as the BM microenvironment provides a protective niche that promotes therapeutic resistance. We developed a simplified, automated and high‐throughput 3D BM co‐culture model that faithfully reproduces key tumour–stroma interactions.
Alex Zadro +12 more
wiley +1 more source
Mantle-derived fluid flux controls Olympic Dam-style Fe oxide-Cu-Au mineralisation. [PDF]
Sci RepThiel S +4 more
europepmc +1 more source
Dynamics of circulating tumour DNA in relapsed/refractory diffuse large B‐cell lymphoma patients
British Journal of Haematology, EarlyView.Summary The response to salvage chemotherapy in relapsed/refractory (R/R) diffuse large B‐cell lymphoma (DLBCL) is poor, and data on circulating tumour deoxyribonucleic acid (ctDNA) in this setting are limited. We evaluated ctDNA dynamics in 29 patients with relapsed or refractory DLBCL who received platinum‐based salvage chemotherapy at the University
Yujie Zhong +9 more
wiley +1 more source
Geophysical Monograph Series, Page 1-26., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Richard E. Ernst +8 more
wiley +2 more sources
Abiotic polycyclic aromatic hydrocarbons originating from the sub-oceanic mantle. [PDF]
Sci RepMitsukawa I +13 more
europepmc +1 more source
Enhanced Core-Mantle Coupling Due to Stratification at the Top of the Core
, 2018 Sebastian Glane, B. A. Buffett
openalex +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Bruton tyrosine kinase (Btk) is essential for B cell function. Its role in myeloid cells is less understood. Greater insights into Btk significance in myeloid cells are needed to evaluate its potential as a therapeutic target during the effector phase of antibody‐induced autoimmune diseases, where inhibiting autoantibody ...
Henning Olbrich +7 more
wiley +1 more source
A Symbolic Return of Communitas William MacDonnell’s Modernizing Mostar [PDF]
, 2015 Craig Leslie Mantle
core +1 more source
Cancer Science, EarlyView.Cancer‐specific antihuman podoplanin antibody chLpMab‐2f exerted antibody‐dependent cellular cytotoxicity and complement‐dependent cytotoxicity against pleural mesothelioma (PM) cell lines. Additionally, chLpMab‐2f inhibited tumor progression in mice with subcutaneously and intrathoracically transplanted human PM cells.
Aito Yoshida +15 more
wiley +1 more source
Cenozoic evolution of earth's strongest geoid low illuminates mantle dynamics beneath Antarctica. [PDF]
Sci RepGlišović P, Forte AM.
europepmc +1 more source