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Central nervous system involvement in mantle cell lymphoma: clinical features, prognostic factors and outcomes from the European Mantle Cell Lymphoma Network

open access: yesAnnals of Oncology, 2013
Central nervous system (CNS) involvement in mantle cell lymphoma (MCL) is uncommon, and the manifestations and natural history are not well described.We present the data on 57 patients with MCL who developed CNS involvement, from a database of 1396 ...
Pavel Klener   +2 more
exaly   +2 more sources

Mantle cell lymphoma

Critical Reviews in Oncology/Hematology, 2012
MCL is a well-characterized clinically aggressive lymphoma with a poor prognosis. Recent research findings have slightly improved the outcome of this neoplasm. The addition of rituximab to conventional chemotherapy has increased overall response rates, but it does not improve overall survival with respect to chemotherapy alone.
Cortelazzo S   +3 more
openaire   +5 more sources

Mantle-cell lymphoma

The Lancet Oncology, 2001
During the past decade, mantle-cell lymphoma has been established as a new disease entity. The normal counterparts of the cells forming this malignant lymphoma are found in the mantle zone of the lymph node, a thin layer surrounding the germinal follicles.
I, Barista   +2 more
openaire   +2 more sources

Treatment of Mantle-Cell Lymphoma

New England Journal of Medicine, 2022
[No Abstract Available]
Burhan, Ferhanoglu   +2 more
openaire   +5 more sources

Mantle cell lymphoma

Current Opinion in Hematology, 2004
Mantle cell lymphoma is the B-cell lymphoma with the worst prognosis. Until now, no standard treatment has resulted in cure. Improvements in understanding of the disease are needed to advance therapeutic efforts.Pathology and immunohistochemistry can identify the subset of patients with the worse prognosis.
Francesco, Bertoni   +2 more
openaire   +2 more sources

Mantle cell lymphomas

1997
MCLs are thought to arise from a subset of B cells that normally express the CD5 antigen and that reside in the mantle zone of secondary lymphoid follicles. Although expression of the CD5 antigen is also seen in small lymphocytic lymphoma and chronic lymphocytic leukemia, MCL differs from SLL/ CLL in several ways.
M A, Rodriguez, W C, Pugh
openaire   +2 more sources

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