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Advances in Anatomic Pathology, 1998
Mantle cell lymphomas comprise 2 to 8% of non-Hodgkin's lymphoma in the United States. They occur in older adults with a distinct male predominance, who present with generalized lymphadenopathy, and often have disseminated disease at the time of diagnosis.
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Mantle cell lymphomas comprise 2 to 8% of non-Hodgkin's lymphoma in the United States. They occur in older adults with a distinct male predominance, who present with generalized lymphadenopathy, and often have disseminated disease at the time of diagnosis.
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Mantle Cell Lymphoma: An Update
Leukemia & Lymphoma, 1992Mantle cell lymphoma is a distinctive pathologic entity that incorporates the previous histopathologic categories of centrocytic lymphoma and lymphocytic lymphoma of intermediate differentiation. These lymphomas are characterized by common histologic and immunologic characteristics that suggest derivation from the follicular mantle zone.
M, Raffeld +3 more
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Mantle cell lymphoma diagnosis
Annales de biologie clinique, 2013Recent classifications of non-Hodgkin's lymphomas based on combination of morphologic, immunophenotypic, and cytogenetic criteria have individualized mantle cell lymphoma (MCL). This clinico-biological entity which accounts for 3 to 10% of all non-Hodgkin's lymphomas, now appears to be a biological and therapeutic model for the understanding and ...
Mohammed, Choukri +7 more
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Autotransplantation for Mantle Cell Lymphoma
The Cancer Journal, 2012Mantle cell lymphoma (MCL) represents about 5% to 9% of all non-Hodgkin lymphomas according to the World Health Organization. The clinical presentation typically consists of diffuse lymphadenopathy and frequent extranodal involvement of the gastrointestinal tract, blood, and bone marrow, as well as frequent splenomegaly.
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The Epigenetics of Mantle Cell Lymphoma
Current Treatment Options in Oncology, 2007There is no consensus treatment for newly diagnosed mantle cell lymphoma. The CHOP + rituximab and hyperCVAD + rituximab regimens are most commonly used. The former is limited by relatively lower rates of complete remission (CR) and frequent relapses. The latter is limited by toxicities, especially in older patients, and relapses that occur later than ...
Margaret, Yu, Elliot, Epner
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Gastrointestinal Endoscopy, 2005
and the pelvis demonstrated no specific findings. At colonoscopy, the ileocecal valve showed an ulcerated growth extending to adjacent cecal wall. This growth showed multiple, irregular, marginated shallow ulcerations (A and B). The histopathology of the biopsied tissue from the ileocecal growth revealed a proliferation of large, atypical lymphoid ...
Michael T, Kram +2 more
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and the pelvis demonstrated no specific findings. At colonoscopy, the ileocecal valve showed an ulcerated growth extending to adjacent cecal wall. This growth showed multiple, irregular, marginated shallow ulcerations (A and B). The histopathology of the biopsied tissue from the ileocecal growth revealed a proliferation of large, atypical lymphoid ...
Michael T, Kram +2 more
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Histopathology of Mantle Cell Lymphoma
Seminars in Hematology, 2011Mantle cell lymphoma (MCL) is a relatively rare lymphoma, accounting for less than 10% only of all lymphomas. Its morphology is quite homogeneous, but it varies strikingly in about 10% of the cases, making the diagnosis of MCL challenging for histopathologists. The definition of the disease was greatly influenced by the discovery of the translocation t(
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MicroRNAs in mantle cell lymphoma
Leukemia & Lymphoma, 2013Mantle cell lymphoma (MCL) is a rare and aggressive subtype of non-Hodgkin lymphoma. New treatment modalities, including intensive induction regimens with immunochemotherapy and autologous stem cell transplant, have improved survival. However, many patients still relapse, and there is a need for novel therapeutic strategies.
Husby, Simon +2 more
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Mantle cell lymphoma: Report of the 2009 Mantle Cell Lymphoma Consortium Workshop
Leukemia & Lymphoma, 2009Mantle cell lymphoma (MCL) is a B-cell non-Hodgkin lymphoma characterized by cyclin D1 overexpression as a result of the t(11;14) chromosomal translocation, and by biological and clinical heterogeneity with frequent extranodal dissemination. There is no consensus or standard for initial therapy or for treatment of relapsed disease, and no proven ...
Michael E, Williams +6 more
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