Results 191 to 200 of about 96,005 (268)

Modeling and Simulation in Development and Regulatory Approval of Chimeric Antigen Receptor T‐Cell Therapies: An Analysis of European Medicines Agency Centralized Procedures From 2018 to 2024

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 4, April 2026.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapies represent a major advancement in oncology. These therapies have demonstrated therapeutic potential, particularly in hematological malignancies where patients have relapsed or are refractory to prior treatments.
Lisa Hanquet, Jean‐Michel Dogné, Flora T. Musuamba   +2 more
wiley   +1 more source

Seismic and mineralogical evidence for an iron-rich mega-ultralow-velocity zone beneath Hawai'i. [PDF]

Sci Adv
Kim D, Song JH, Dobrosavljevic VV, Lekić V.   +3 more
europepmc   +1 more source

Disaggregation of Landslide Risk

Earth's Future, Volume 14, Issue 4, April 2026.
Abstract Quantifying and disaggregating landslide risk through probabilistic landslide risk analysis (PLRA) is critical for land use regulation and risk reduction. However, no transferable model for PLRA currently exists that resolves landslide consequences to individual buildings at regional scales.
William Pollock, Joseph Wartman
wiley   +1 more source

Bedrock uplift reduces Antarctic sea-level contribution over next centuries. [PDF]

Nat Commun
van Calcar CJ, Bernales J, Berends CJ, van der Wal W, van de Wal RSW.   +4 more
europepmc   +1 more source

Holocene Normal Faulting in the Southern Rocky Mountain Trench; Orogenic Collapse Modulated by Glacial Unloading?

Journal of Geophysical Research: Solid Earth, Volume 131, Issue 4, April 2026.
Abstract The Southern Rocky Mountain Trench (SRMT) is a conspicuous valley in the eastern Canadian Cordillera. It lies above a sharp change in lithospheric strength and thickness and is occupied by a normal fault thought to have last been active in the Eocene.
T. Finley, E. Nissen, L. J. Leonard, J. F. Cassidy, V. Prush, B. Miller   +5 more
wiley   +1 more source

Long-term history of continental weathering and particle transport to the sea. [PDF]

Proc Natl Acad Sci U S A
Canfield DE, Zhang S, Mitchell RN, Wang X, Naemi A, Spencer CJ, Zhang P.   +6 more
europepmc   +1 more source

Autocorrelation‐Based Imaging of Crustal Discontinuities Including the Main Himalayan Thrust and Vp/Vs Ratio in the Jammu and Kashmir Himalaya

Journal of Geophysical Research: Solid Earth, Volume 131, Issue 4, April 2026.
Abstract The Jammu and Kashmir Himalaya, located between the rupture zones of the 1905 Kangra and 2005 Kashmir earthquakes, represent a prominent “seismic gap” where understanding the subsurface structure is critical for seismic hazard assessment. This study presents new insights into the crustal structure of this region using teleseismic P‐wave coda ...
Hari Ram Thapa, Supriyo Mitra, Abdelkrim Aoudia, Gordana Vlahovic, Keith Priestley, Sunil Kumar Wanchoo   +5 more
wiley   +1 more source

Water Versus Land on Temperate Rocky Planets. [PDF]

Space Sci Rev
Guimond CM, Spohn T, Berdyugina S, Byrne PK, Coltice N, Glaser DM, Lingam M, Lineweaver CH, Cawood PA.   +8 more
europepmc   +1 more source

Fault Friction, Plate Rheology, and Mantle Torques From a Global Dynamic Model of Neotectonics

Journal of Geophysical Research: Solid Earth, Volume 131, Issue 4, April 2026.
Abstract Improvements in software, parallel computing, global data sets, and laboratory flow‐laws help to develop the global Earth5 thin‐shell finite‐element model of Bird et al. (2008, https://doi.org/10.1029/2007jb005460) into a benchmark study. All experiments confirm that modeled faults (other than megathrusts) have low effective friction of 0.085 ±
Peter Bird, Jon Bryan May, Michele M. C. Carafa   +2 more
wiley   +1 more source

Linking electrical anomalies in the upper mantle to petrological and geochemical heterogeneities. [PDF]

Natl Sci Rev
Yang X, Xu YG, Xia QK.
europepmc   +1 more source