Results 101 to 110 of about 771,265 (286)

Emollient Formulations and Skin Barrier Practices in the Context of Eczema and Food Allergy Prevention

Allergy, EarlyView.
ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj, Donald Y. M. Leung, Carina Venter, Barbara Sozańska, Helen A. Brough   +4 more
wiley   +1 more source

Re-os isotope constraints on the age of the Lithospheric mantle beneath western Greenland. [PDF]

, 2007
Alkaline magmatic activity across Western Greenland (W.G.) provides a record of lithosphere evolution over the last 600 Ma. Ultra Mafic Lamprophyre (UML) magmatism in particular has erupted an exceptional inventory of mantle xenoliths allowing a detailed
Webb, Michelle
core  

Morphology and tectonics of the Mid-Atlantic Ridge, 7°–12°S

, 2003
We present swath bathymetric, gravity, and magnetic data from the Mid-Atlantic Ridge between the Ascension and the Bode Verde fracture zones, where significant ridge–hot spot interaction has been inferred.
T. A. Minshull, Brozena, J.M., N. J. Bruguier, Minshull, T.A., J. M. Brozena, Bruguier, N.J.   +5 more
core   +1 more source

Dispersal, source and glass chemistry of a third tephra unit within Iceland's Settlement Layer

Boreas, EarlyView.
Tephra layers may be studied to understand the dynamics and sequence of past explosive volcanism. In Iceland, the distinctive Settlement Layer (AD ~877) underlies almost all archaeological evidence for the Norse Settlement and is preserved in soils across Iceland and as cryptotephra overseas.
Conner A. G. Morison, Guðrún Larsen, Anthony J. Newton, Andrew J. Dugmore   +3 more
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Time constraints on the formation of lithospheric mantle beneath cratons: a re-Os isotope and platinum group element study of peridotite xenoliths from northern Canada and Lesotho, [PDF]

, 2001
Understanding the generation and evolution of cratonic lithospheric keels requires detailed knowledge of their age, timescale of formation, and the relationship between the crust and mantle part of the lithosphere.
Irvine, Gordon James
core  

Mitochondrial Morphology Dynamics Remodel Metabolism and Affect TKI Sensitivity in EGFR‐Mutated Lung Cancer

Cancer Science, EarlyView.
TKI treatment promotes mitochondrial fission and metabolic reprogramming toward oxidative phosphorylation in residual EGFR‐mutant lung cancer cells. Targeting this metabolic vulnerability restores TKI sensitivity and provides a promising strategy to overcome acquired resistance.
Yu Zhao, Yuqiang Liu, Mingxuan Xie, Zhiming Ye, Hong Huang, Maojin Yao, Feng Zhou, Jianzhu Zhao, Jun Tang   +8 more
wiley   +1 more source

The Use of Azimuthal Variation in ScS–S Differential Travel Times to Investigate Possible Anisotropy in the Lowermost Mantle Beneath the Philippines

Geosciences
We collected approximately 500 ScS–S differential travel times passing beneath the Philippines with various azimuths to discuss whether there were azimuthal variations in the ScS–S time residuals.
Satoru Tanaka
doaj   +1 more source

Clues of ancient incomplete lineage sorting during bivalve evolution undermine support for Heterodonta

Cladistics, EarlyView.
Abstract A long‐standing challenge in phylogenomics has been the resolution of relationships originated from ancient radiations. In these cases, phenomena such as incomplete lineage sorting can increase the support for conflicting resolutions. Most of the diversity in the Class Bivalvia originated during an Ordovician radiation; indeed, several deep ...
Alessandro Formaggioni, Takeshi Takeuchi, Mayuko Hamada, Kazuhiro Saito, Tatsuya Sakamoto, Noriyuki Satoh, Federico Plazzi, Marco Passamonti   +7 more
wiley   +1 more source

Is the Deep Martian Mantle Heterogeneous? A Reappraisal of Seismological Evidences

Geophysical Research Letters
It has been proposed that the deep Martian mantle contains distributed heterogeneities preserved since the accretion of the planet. This result relies on a multiple‐scattering interpretation of frequency‐dependent arrival times of P‐waves detected in the
L. Margerin
doaj   +1 more source