Results 31 to 40 of about 479 (137)

Slab Transport of Fluids to Deep Focus Earthquake Depths—Thermal Modeling Constraints and Evidence From Diamonds

AGU Advances, 2021
The nature and cause of deep earthquakes remain enduring unknowns in the field of seismology. We present new models of thermal structures of subducted slabs traced to mantle transition zone depths that permit a detailed comparison between slab pressure ...
Steven B. Shirey, Lara S. Wagner, Michael J. Walter, D. Graham Pearson, Peter E. van Keken   +4 more
doaj   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Seismic evidence of the Hainan mantle plume by receiver function analysis in southern China

Geophysical Research Letters, 2016
The Lei‐Qiong region is the largest igneous province in southern China and may be a surface expression of a mantle plume beneath the region (the Hainan mantle plume).
S. Shawn Wei, Y. John Chen
doaj   +1 more source

Constraining composition and temperature variations in the mantle transition zone

Nature Communications, 2022
A new study by @JinZhang_MP models the global distribution of wadsleyite proportion, temperature and water content in the upper mantle transition zone.
Wen-Yi Zhou, Ming Hao, Jin S. Zhang, Bin Chen, Ruijia Wang, Brandon Schmandt   +5 more
doaj   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Upwellings and Mantle Ponding Zones in the Lower Mantle Transition Zone (660–1000 km)

Geosciences
Convective instabilities at various boundary layers in the earth’s mantle—including the core–mantle boundary, mantle transition zone and lithosphere-asthenosphere boundary— result in upwellings (mantle plumes) and downwellings (subducting slabs).
Jean-Paul Montagner, Barbara Romanowicz, Mathurin Wamba, Gael Burgos   +3 more
doaj   +1 more source

A General Workflow for Tangential Flow Filtration Perfusion Scale‐Up

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Tangential flow filtration (TFF) perfusion using hollow‐fiber modules offers substantial advantages over other mammalian cell retention technologies. Recently, increased awareness of Starling flow has helped to enhance filtration performance to similar, or even higher levels compared to alternative technologies.
Patrick Romann, Ken Lee, Venkatesh Natarajan, Daniel Ley, Claes Nymand Nilsson, David Garcia‐Munzer, Dominik Schieman, Mahbod Hajighasemi, Alex Zaytsev, Jason Friedman, Loic Chappuis, Tobias Habicher, Colin Jaques, Alex Cohen, Matthew Gagnon, Edward Chan, Daniel J. Karst, Philip Giller, Antony Sibilia, Andrew L. Zydney, Thomas K. Villiger   +20 more
wiley   +1 more source

Peroxodisulfate‐Enhanced Leaching of Deep‐Sea Manganese Crusts and Sulfides

Chemie Ingenieur Technik, EarlyView.
Ammonium peroxodisulfate enables efficient leaching of deep‐sea manganese crusts and massive sulfides while offering electrolytic recycling. High leaching yields for V, Mn, Co, Mo, Sn, and W, along with complete leaching of As and Sb, highlight its potential as a powerful and sustainable oxidant for marine resource processing.
Bastian Hansel, Lucas Thumeyer, Ebbe H. Hartz, Håvard Hallås Stubseid, Peter Fröhlich, Martin Bertau   +5 more
wiley   +1 more source

Speed structure of the mantle under the Dnieper-Donets Depression and its surroundings. Part I

Геофизический журнал, 2020
The article discusses the high-speed structure of the mantle under the Dnieper-Donets Depression (DDD). The solution obtained by the Taylor approximation of the solution of the three-dimensional seismic tomography problem is used.
T.A. Tsvetkova, I.V. Bugaenko, L.N. Zaets   +2 more
doaj   +1 more source

Assessment of Gibbs Free Energy Calculation in PI‐Controlled Heating

Chemie Ingenieur Technik, EarlyView.
For description and control of chemical processes in lab or industry thermodynamic variable Gibbs free energy provides opportunity to compare and interpret phenomena, even on a quantitative level. In a case study for PI‐controlled heating, impacts on its limits from control delay until parameter quantization are highlighted and assessed.
Jannik Dutschke, Samira Johanna Geiger, Liane Andrea Haufe, Sebastian Kaiser, Markus Seifert   +4 more
wiley   +1 more source