Results 161 to 170 of about 102,581 (254)

Updated Gene Prediction of the Cucumber (9930) Genome through Manual Annotation. [PDF]

Plants (Basel)
Du W, Xia L, Li R, Zhao X, Jin D, Wang X, Pei Y, Zhou R, Chen J, Yu X.   +9 more
europepmc   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Quantifying Variability of Manual Annotation in Cryo-Electron Tomograms. [PDF]

Microsc Microanal, 2016
Hecksel CW, Darrow MC, Dai W, Galaz-Montoya JG, Chin JA, Mitchell PG, Chen S, Jakana J, Schmid MF, Chiu W.   +9 more
europepmc   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Diaci v3.0: chromosome-level assembly, de novo transcriptome, and manual annotation of Diaphorina citri, insect vector of Huanglongbing. [PDF]

Gigascience
Shippy TD, Hosmani PS, Flores-Gonzalez M, Mann M, Miller S, Weirauch MT, Vosberg C, Massimino C, Tank W, de Oliveira L, Chen C, Hoyt S, Adams R, Adkins S, Bailey ST, Chen X, Davis N, DeLaFlor Y, Espino M, Gervais K, Grace R, Harper D, Hasan DL, Hoang M, Holcomb R, Jernigan MR, Kemp M, Kennedy B, Kercher K, Klaessan S, Kruse A, Licata S, Lu A, Masse R, Mathew A, Michels S, Michels E, Neiman A, Norman S, Norus J, Ortiz Y, Panitz N, Paris T, Perentesis KMR, Perry M, Reynolds M, Sena MM, Tamayo B, Thate A, Vandervoort S, Ventura J, Weis N, Wise T, Shatters RG, Heck M, Benoit JB, Hunter WB, Mueller LA, Brown SJ, D'Elia T, Saha S.   +60 more
europepmc   +1 more source

MRI FLAIR lesion segmentation in multiple sclerosis: Does automated segmentation hold up with manual annotation? [PDF]

Neuroimage Clin, 2017
Egger C, Opfer R, Wang C, Kepp T, Sormani MP, Spies L, Barnett M, Schippling S.   +7 more
europepmc   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

A Combined Manual Annotation and Deep-Learning Natural Language Processing Study on Accurate Entity Extraction in Hereditary Disease Related Biomedical Literature. [PDF]

Interdiscip Sci
Huang DL, Zeng Q, Xiong Y, Liu S, Pang C, Xia M, Fang T, Ma Y, Qiang C, Zhang Y, Zhang Y, Li H, Yuan Y.   +12 more
europepmc   +1 more source

PacBio assembly of a Plasmodium knowlesi genome sequence with Hi-C correction and manual annotation of the SICAvar gene family. [PDF]

Parasitology, 2018
Lapp SA, Geraldo JA, Chien JT, Ay F, Pakala SB, Batugedara G, Humphrey J, MaHPIC consortium, DeBARRY JD, Le Roch KG, Galinski MR, Kissinger JC.   +11 more
europepmc   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source