Results 211 to 220 of about 1,450,549 (348)

MMP9High Neutrophils are Critical Mediators of Neutrophil Extracellular Traps Formation and Myocardial Ischemia/Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
During a heart attack, neutrophils rapidly activate and differentiate into a specific subset characterized by high levels of MMP9, a tissue‐damaging enzyme, via the SPI1/CST7 pathway. These neutrophils form harmful net‐like structures (Neutrophil extracellular traps, NETs) that exacerbate heart injury.
Shiyu Hu   +13 more
wiley   +1 more source

Robotics for Neuroendovascular Therapy. [PDF]

open access: yesJ Neuroendovasc Ther
Miyachi S   +3 more
europepmc   +1 more source

Chronic, Battery‐Free, Fully Implantable Multimodal Spinal Cord Stimulator for Pain Modulation in Small Animal Models

open access: yesAdvanced Science, EarlyView.
This work introduces wireless‐powered fully implantable spinal cord stimulation (SCS) in freely moving animal models, supporting diverse ethological paradigms. kHz stimulation with real‐time digital programming offers versatile, dynamically optimized therapy. Scalable fabrication ensures high N studies and seamless translation.
Allie J. Widman   +11 more
wiley   +1 more source

A Solution‐Based Deposition Method Enabling Pigment Blue Edible Electrochemical Transistors

open access: yesAdvanced Science, EarlyView.
A novel solution‐based method is presented to produce Copper Phthalocyanine fibrous films displaying effective ion permeability and enhanced transconductance in electrolyte‐gated transistors architectures. Using these films, the first instance of a fully edible electrolyte‐gated transistor with volumetric capacitance, targeting in‐body applications, is
Alessandro Luzio   +10 more
wiley   +1 more source

M2 Macrophage‐Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1hi Neutrophils to Enhance Inflamed Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This study reveals that M2‐EVs mitigate periodontitis‐induced bone resorption by modulating neutrophil fate. Single‐cell RNA sequencing identified an Anxa1hi neutrophil subpopulation with pro‐reparative properties. M2‐EVs disrupt neutrophil maturation, promoting this subpopulation through key reprogramming genes (Acvrl1, Fpr2). These findings highlight
Yufei Yao   +7 more
wiley   +1 more source

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