Results 71 to 80 of about 6,153,094 (384)

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Efficacy of a self-help manual in increasing resilience in carers of adults with depression in Thailand [PDF]

open access: yes, 2016
Caring for a person with a mental illness can have adverse effects on caregivers; however, little is known about how best to help such caregivers. The aim of the present study was to examine the efficacy of a cognitive behaviour therapy-guided self-help ...
Fan Y. C.   +9 more
core   +1 more source

Effectiveness of manual therapy to the cervical spine with and without manual therapy to the upper thoracic spine in the management of non-specific neck pain; a randomized controlled trial.

open access: yesJPMA. The Journal of the Pakistan Medical Association, 2020
Objectives To compare the effectiveness of manual therapy to the cervical spine with and without manual therapy to the upper thoracic spine in the management of non-specific neck pain.
Aatik Arsh   +5 more
semanticscholar   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Development of the “Treatment beliefs in knee and hip OsteoArthritis (TOA)” questionnaire

open access: yesBMC Musculoskeletal Disorders, 2017
Background Use of conservative treatment modalities in osteoarthritis (OA) is suboptimal, which appears to be partly due to patients’ beliefs about treatments.
Ellen M. H. Selten   +7 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Comparative study between the effects of isolated manual therapy techniques and those associated with low level laser therapy on pain in patients with temporomandibular dysfunction [PDF]

open access: yes, 2008
Objective: This study sought to evaluate the pain condition in patients with temporomandibular dysfunction after applying manual therapy techniques and those associated with this low level laser therapy.
Juliana Cristina Frare   +1 more
core  

The evolution of manual therapy education: what are we waiting for?

open access: yesJournal of Manual & Manipulative Therapy, 2020
ISSN: 1066-9817 (Print) 2042-6186 (Online) Journal homepage: https://www.tandfonline.com/loi/yjmt20 The evolution of manual therapy education: what are we waiting for? William H.
W. Kolb   +3 more
semanticscholar   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Analysis of the Effect of Training Driving on Electromyographic Parameters in Trained Karting Drivers: A Study of Fatigue and Its Relationship with Training Practice

open access: yesJournal of Functional Morphology and Kinesiology
Objectives: The present study aimed to investigate changes in forearm muscle activity associated with short-term go-kart driving (680 m) and its potential effect on muscle activation patterns. Methods: Eleven male karting league drivers (mean age: 23.18 ±
Aleksander Zarębski   +3 more
doaj   +1 more source

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