Results 51 to 60 of about 380,691 (310)

Health Hazard Manual For Cutting Oils, Coolants, and Metalworking Fluids [PDF]

, 1991
[Excerpt] The metalworker can be exposed to cutting oils during application by two basic routes of entry: skin contact and inhalation. The higher risk jobs tend to be those with high cutting speeds, heavy oil flow, and continuous contact, which may ...
Brown, Nellie J
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

American way of drawing: American manuals in the design of the military bases in Spain

Cuadernos de Proyectos Arquitectónicos, 2018
In the elaboration of the plans for the military bases, built by Americans and Spaniards in Spain in the 50s, the American military design manuals were used.
María del Pilar Salazar
doaj  

Crisis Management [PDF]

, 2019
[Excerpt] It’s no longer a matter of WHETHER a crisis will happen or not, it’s a matter of WHAT TYPE it is and WHEN it occurs. An organization (and its union) that can manage and recover from a crisis demonstrates competence – the results can mean ...
Brown, Nellie J
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Health Hazard Manual for Firefighters [PDF]

, 1990
[Excerpt] Firefighters, as well as victims, can be exposed to a variety of toxic substances during a fire. Some of these toxicants are particularly insidious because they are produced by thermal decomposition before smoke makes a fire ...
Brown, Nellie J.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Equestrian Bridges and Underpasses

Urban Science
Areas with well-developed networks of equestrian routes attract riders, contributing to tourism development and boosting the economy. As the most critical elements of equestrian routes are road, railway, and watercourse crossings, the construction of ...
Ivana Štimac Grandić
doaj   +1 more source

Adapting sensory integration theory terminology into Estonian based on the assessment tools Evaluation in Ayres Sensory Integration, Sensory Profile 2, and Adolescent/Adult Sensory Profile [PDF]

Proceedings of the Estonian Academy of Sciences
Sensory integration theory elucidates the relationship between the human nervous system’s capacity to process and integrate sensory sensations and behaviour.
Hanna-Maria Põldma, Grete Eiche, Jaanika Savolainen, Kristiina Puura, Õie Tähtla   +4 more
doaj   +1 more source