Results 61 to 70 of about 380,691 (310)

Occupational Asthma or Work-Related Exacerbation of Asthma [PDF]

open access: yes, 2019
[Excerpt] Occupational asthma is asthma due to work exposures. It can be caused by a specific workplace agent with a specific immune system response – the agent is called a sensitizer.
Brown, Nellie J
core   +1 more source

Manual Training and Manual Labor [PDF]

open access: yesThe Elementary School Teacher, 1904
THE march of manual training in the educational world is rivaled by the retreat of manual labor in the industrial world. At first glance the general situation seems to be something of an anomaly. The tremendous development of machinery and applied science in the industrial world has crowded in between the brain and the hand, feeding on both ...
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Training manuals for nondestructive testing using magnetic particles [PDF]

open access: yes, 1968
Training manuals containing the fundamentals of nondestructive testing using magnetic particle as detection media are used by metal parts inspectors and quality assurance specialists. Magnetic particle testing involves magnetization of the test specimen,

core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Merck Manuals

open access: yesJournal of the Medical Library Association, 2017
None
Krystal Bullers
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

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