Results 61 to 70 of about 1,017,349 (300)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Manufacturing renaissance

open access: yes, 2013
Manufacturing Renaissance, i.e. return of manufacturing to west, has been recently observed. This paper analyzes the patterns observed within each of the four main drivers behind this new phenomenon and delves more deeply into the driver that centers on the new manufacturing technologies such as Additive Manufacturing (AM) and 3D Printing.
Kianian, Babak   +2 more
openaire   +4 more sources

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Multi-objective optimization of the hollow shaft direct drive motor

open access: yesAdvances in Mechanical Engineering, 2023
Surface permanent magnet synchronous motor (SPMSM) is widely used in low-speed and high torque permanent magnet synchronous motor. A multi-objective optimization method of hollow shaft direct drive motor (HSDDM) for double direct drive feed system (DDFS)
Zhaoguo Wang, Jingyu Gong, Bei Liu
doaj   +1 more source

Manufacturing doubt [PDF]

open access: yesJournal of Environmental Economics and Management, 2018
In their efforts to affect regulations, firms have developed specific strategies to exploit scientific uncertainty. They have manufactured doubt by hiring and funding dissenting scientists, by producing and publicizing favorable scientific findings and by generally concealing their involvement in biased research.
Bramoullé, Yann, Orset, Caroline
openaire   +5 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Supreme Laundry

open access: yes, 1910
Terminal Building, 15th St. on waterfront, Remington Arms during WWI, purchased by Thomas Lipton, tea manufacturer.

core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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