Results 51 to 60 of about 234,407 (305)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Is Eighth District manufacturing endangered? [PDF]
Manufactures ; Federal Reserve District ...
Thomas B. Mandelbaum
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
An Intelligent Matching System for the Products of Small Business/Manufactures with the Celebrities
With the development of ICT, e-business have brought consumers opportunities to choose a wider range of products to purchase. However, these opportunities made it difficult for them to make a choice.
Jeong Junho +3 more
doaj +1 more source
Improving production management [PDF]
Production (Economic theory) ; Manufactures ...
Donald S. Allen
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The cyclicality of cash flow and investment in U.S. manufacturing [PDF]
Cash flow ...
Bruce C. Petersen, William A. Strauss
core
Useful knowledge, 'industrial enlightenment', and the place of India [PDF]
Research is now turning to the missing place of technology and ‘useful knowledge’ in the debate on the ‘great divergence’ between East and West. Parallel research in the history of science has sought the global dimensions of European knowledge.
Angerstein +34 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

