Results 211 to 220 of about 2,561,996 (344)

Enabling access to genetically modified cell therapies through flexible approaches to manufacturing and cost recovery. [PDF]

J Immunother Cancer
Stewart MD, Cabanski CR, Allen JD, Connolly JE, Beneski BM, Dropulić B, Feldman SA, Fleisher LA, Hanley PJ, Hege K, Kekre N, Fernandez Lynch H, Mackall CL.   +12 more
europepmc   +1 more source

Incremental Manufacturing: Model-based part design and process planning for Hybrid Manufacturing of multi-material parts

, 2019
Ann-Kathrin Reichler, Roman Gerbers, Paul Falkenberg, Eiko Türk, Franz Dietrich, Thomas Vietor, Klaus Dröder   +6 more
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Advancing AAV vector manufacturing: challenges, innovations, and future directions for gene therapy. [PDF]

Front Mol Med
Kowshik NCSS, Singh P.
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Software-defined self-learning control system for industrial robots by using reinforcement learning. [PDF]

Sci Rep
Moon J, Kim M, Lee T, Um J.
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Integration of safety and sustainability criteria into early design stages of battery cell manufacturing machinery. [PDF]

Sci Rep
Cerrillo C, Mendoza G, Ormazabal G, Popok V, Oetting H, Konersmann B, Tedeschi Gallo A, Lavigne Philippot M.   +7 more
europepmc   +1 more source

Parametric Energy Consumption Modeling for Cathode Coating Manufacturing of Lithium-Ion Batteries

, 2020
Kai Zhou, Yongjian Su, Weiwei Liu, Yelin Deng   +3 more
openalex   +1 more source