Results 31 to 40 of about 2,561,996 (344)
Culture, Medicine and Psychiatry, 2006 The Food and Drug Administration (FDA) has declared that it would be illegal to advertise as or in any way claim your drug to be superior to competitors on the market, which are up to 30 times cheaper. How does a pharmaceutical company market such a product? The answer is to enlist academics to form expert panels to construct guidelines and algorithms,
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed +5 more
wiley +1 more source
IEEE Access, 2019 Tool wear monitoring is a typical multi-sensor information fusion task. The handcrafted features may be a suboptimal choice that will lower the monitoring accuracy and require significant computational costs that hinder the real-time applications.
Zhiwen Huang +4 more
doaj +1 more source
Additive manufacturing by digital light processing: a review
Progress in Additive Manufacturing, 2022 Additive manufacturing is a layer-by-layer strategy enabling the advanced design and fabrication of complex 3D objects and structures, overcoming geometry limitations and reducing waste production compared to conventional technologies.
R. Chaudhary +5 more
semanticscholar +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Embedding a commitment to equitable global access into basic and early-phase translational research
Journal of Clinical and Translational ScienceThe COVID-19 pandemic laid bare the inequities in U.S. healthcare in ways that captured public attention and reinforced the need to view all of healthcare through an equity lens. It also exposed global inequities in access to healthcare technologies.
Barry S. Coller
doaj +1 more source
Machine learning in manufacturing and industry 4.0 applications
International Journal of Production Research, 2021 The machine learning (ML) field has deeply impacted the manufacturing industry in the context of the Industry 4.0 paradigm. The industry 4.0 paradigm encourages the usage of smart sensors, devices, and machines, to enable smart factories that ...
Rahul Rai +3 more
semanticscholar +1 more source
International Journal of Production Research, 2018 This paper introduces anarchic manufacturing, an extremely distributed planning and control philosophy, as the methodology for planning and controlling future smart factories. Anarchic manufacturing delegates decision-making authority and autonomy to the lowest level of entities in system elements with no centralised control or oversight.
Ma, Andrew +2 more
openaire +3 more sources
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source