Results 71 to 80 of about 1,654,996 (316)

Jeffrey Manufacturing Company Employment Office

open access: yes, 1919
Two women at desks and one at file cabinet in the Jeffrey Manufacturing Company employment office ...
Jeffrey Manufacturing Company
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Manufactured Inequality [PDF]

open access: yesJournal of Labor Economics, 1997
Many discrete life choices--where to live, what kind of job to hold, and consumption lifestyle--are stratified by income. Stratification and sorting often manifest state-dependent preferences in which the marginal utility of income (consumption) depends on the outcome of prior choices.
openaire   +1 more source

Jeffrey Manufacturing Company advertisement

open access: yes, 1967
This advertisement for the Jeffrey 300-U coal-cutter features an alligator and reads "Meet the world's fastest cutter." The ad was produced by the Jeffrey Manufacturing Company of Columbus, Ohio, and dates to ...
Jeffrey Manufacturing Company
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Jeffrey Manufacturing Company headquarters photograph

open access: yes, 1940
Exterior view photograph of the Jeffrey Manufacturing Company headquarters on First Avenue, Columbus, Ohio, ca. 1946. Jeffery Manufacturing started in 1877 as Lechner Mining Machine Co.
Jeffrey Manufacturing Company
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Additive manufacturing: the future of manufacturing

open access: yesMateriali in tehnologije, 2017
Abstract: Additive manufacturing process is an advanced manufacturing method that is used to fabricate prototypes, tooling, as well as functional product. Additive manufacturing process can produce complex part as a single unit object that was not possible with the traditional manufacturing methods.
Adekanye, Adefemi   +3 more
openaire   +1 more source

Jeffrey Manufacturing Company Headquarters

open access: yes, 1947
Photograph of the lobby at the Jeffrey Manufacturing Company headquarters, Columbus, Ohio, 1947. Behind the secretary is a bronze plaque of the company founder, Joseph A. Jeffrey.
Jeffrey Manufacturing Company
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy