Results 151 to 160 of about 4,830,203 (376)
A Student-Centered Learning Approach to Design for Manufacturability: Meeting the Needs of an Often- Forgotten Customer [PDF]
, 2018 A hands-on learning module was implemented at Marquette University in 2012 to teach biomedical engineering students about basic manufacturing processes, lean manufacturing principles, and design for manufacturability.
Goldberg, Jay R., Rank, David
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Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Machine Design Experiments Using Gears to Foster Discovery Learning [PDF]
, 2015 Machine Design Experiments Using Gears to Foster Discovery Learning For the typical undergraduate engineering student the topic of gears is introduced and discussed in several courses.
Nagurka, Mark L. +1 more
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Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Annual technical report, fiscal year 1979. Volume 1: Executive summary [PDF]
Accomplishments of the Point-Focusing Distributed Receiver Technology project are presented. The following aspects of the project are discussed: information dissemination, concentrator development, receiver and heat transport network development, power ...
Lucas, J. W.
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Jobs from Renewable Energy and Energy Efficiency [PDF]
, 2008 According to research by Roger Bezdek for the American Solar Energy Society (ASES), the renewable energy (RE) and energy efficiency (EE) industries created a total of 8.5 million jobs (direct and indirect) in 2006; 450,000 jobs in RE and 8 million jobs ...
Amy Sauer +3 more
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A Physics-Informed Machine Learning Approach for Solving Heat Transfer Equation in Advanced Manufacturing and Engineering Applications [PDF]
Engineering applications of artificial intelligence, 2020 N. Zobeiry, K. D. Humfeld
semanticscholar +1 more source
Molecular Oncology, EarlyView.Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan +4 more
wiley +1 more source
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source